538909

Prostaglandin D₂

≥98% (HPLC), adenylate cyclase activator, solid

• Synonym(e): Prostaglandin D₂, PGD₂
• Empirische Formel (Hill-System): C₂₀H₃₂O₅
• CAS-Nummer: 41598-07-6
• Molekulargewicht: 352.47
• UNSPSC Code: 12352211
• NACRES: NA.77
• MDL number: MFCD00077857
• eCl@ss: 42020658
• Assay: ≥98% (HPLC)
• Form: solid
• Storage condition: OK to freeze

Eigenschaften

• Produktname: Prostaglandin D₂, Major prostaglandin metabolite in brain and an important inflammatory mediator in mast cells.
• Quality Segment: 100
• description: Merck USA index - 14, 7879
• assay: ≥98% (HPLC)
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze
• color: white
• solubility: ethanol: 100 mg/mL, acetone: soluble, ethyl acetate: soluble, methanol: soluble
• shipped in: wet ice
• storage temp.: −20°C
• SMILES string: O[C@@H]1[C@@H]([C@H](C(=O)C1)\C=C\[C@@H](O)CCCCC)C\C=C/CCCC(=O)O
• InChI: 1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-18,21-22H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,18-/m0/s1
• InChI key: BHMBVRSPMRCCGG-OUTUXVNYSA-N

Beschreibung

General description

Major prostaglandin metabolite in the brain and an important inflammatory mediator in mast cells. Neuromodulator that evokes nerve-mediated Cl^- secretion. Stimulates adenylate cyclase.

Biochem/physiol Actions

Cell permeable: no

Primary Target
Adenylate cyclase

Product does not compete with ATP.

Reversible: no

Preparation Note

Following reconstitution, aliquot and freeze (-20°C).

Other Notes

Horn, E.H., et al. 1995. Clin. Sci. 89, 91.
Frieling, T., et al. 1994. Am. J. Physiol. 266, G132.
Huttemeier, P.C., et al. 1993. Prostaglandins 45, 177.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Harmful (C)

Sicherheitshinweise

• pictograms: GHS08,GHS07
• signalword: Danger
• hcodes: H302,H360
• pcodes: P202 - P264 - P280 - P301 + P312 - P308 + P313 - P405
• Hazard Classifications: Acute Tox. 4 Oral - Repr. 1B
• Lagerklasse: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable