474500

4-Methylumbelliferyl-N-acetyl-α-D-glucosaminid

Single spot by TLC, solid, N-acetyl-α-D-glucosaminidase substrate, Calbiochem^®

• Synonym(e): 4-Methylumbelliferyl-N-acetyl-α-D-glucosaminid, 4-Methylumbelliferyl-2-Acetamid-2-Desoxy-α-D-Glucopyranosid
• Empirische Formel (Hill-System): C₁₈H₂₁NO₈
• CAS-Nummer: 80265-04-9
• Molekulargewicht: 379.36
• MDL number: MFCD00036771
• UNSPSC Code: 51111800
• NACRES: NA.21
• Form: solid
• Quality level: 100
• Storage condition: OK to freeze, desiccated, protect from light

Eigenschaften

• Produktname: 4-Methylumbelliferyl-N-acetyl-α-D-glucosaminid, Ultrasensitive, fluorogenic substrate for assay of N-acetyl-α-D-glucosaminidase. Can be used to test for Sanfilippo syndrome B.
• Quality Level: 100
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze, desiccated, protect from light
• impurities: <0.05% 4-methylumbelliferone, <0.2% β-anomer
• color: white
• solubility: DMF: soluble, DMSO: soluble
• shipped in: ambient
• storage temp.: 10-30°C
• SMILES string: N([C@H]1[C@H](O[C@@H]([C@H]([C@@H]1O)O)CO)Oc2cc3[o][c](cc(c3cc2)C)=O)C(=O)C
• InChI: 1S/C18H21NO8/c1-8-5-14(22)26-12-6-10(3-4-11(8)12)25-18-15(19-9(2)21)17(24)16(23)13(7-20)27-18/h3-6,13,15-18,20,23-24H,7H2,1-2H3,(H,19,21)/t13-,15-,16-,17-,18+/m1/s1
• InChI key: QCTHLCFVVACBSA-FGTAOJJYSA-N

Beschreibung

General description

Ultrasensitives, fluorogenes Substrat für N-Acetyl-α;-D-Glucosaminidase-Tests. Kann zum Testen auf das Sanfilippo-B-Syndrom verwendet werden. Anregungsmaximum: 360 nm; Emissionsmaximum: 440 nm.

Preparation Note

In Lösung instabil; direkt vor der Verwendung rekonstituieren.

Analysis Note

Einzelpunkt mittels TLC

Other Notes

Marsh, J., and Fensom, A.H. 1985. Clin. Genet.27, 258.
Chow, P., and Weissmann, B. 1981. Carbohydr. Res. 96, 87.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxizität: Standard-Handhabung (A)

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable