345836

Genistin

An isoflavone glycoside found in soy-based food products.

• Synonym(e): Genistin, Genistein, 7-O-β-D-Glucopyranoside
• Empirische Formel (Hill-System): C₂₁H₂₀O₁₀
• CAS-Nummer: 529-59-9
• Molekulargewicht: 432.38
• UNSPSC Code: 12352200
• NACRES: NA.77
• MDL number: MFCD00016883
• Assay: ≥95% (HPLC)
• Form: solid
• Storage condition: OK to freeze, protect from light

Eigenschaften

• Quality Segment: 100
• description: Merck USA index - 14, 4399
• assay: ≥95% (HPLC)
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze, protect from light
• color: off-white to light yellow
• solubility: DMSO: 10 mg/mL
• shipped in: ambient
• storage temp.: −20°C
• SMILES string: O1[C@H]([C@@H]([C@H]([C@@H]([C@H]1CO)O)O)O)Oc2cc3[o]cc([c](c3c(c2)O)=O)c4ccc(cc4)O
• InChI: 1S/C21H20O10/c22-7-15-18(26)19(27)20(28)21(31-15)30-11-5-13(24)16-14(6-11)29-8-12(17(16)25)9-1-3-10(23)4-2-9/h1-6,8,15,18-24,26-28H,7H2/t15-,18-,19+,20-,21-/m1/s1
• InChI key: ZCOLJUOHXJRHDI-CMWLGVBASA-N

Beschreibung

General description

An isoflavone glycoside found in soy-based food products. This is an inactive analog of the PTK inhibitor Genistein (Cat. No. 345834) and can be used as a negative control for Genistein. Reported to reduce bone loss in ovarectomized rats.

Inactive analog of the protein tyrosine kinase inhibitor Genistein (Cat. No. 345834) that can be used as a negative control compound. An isoflavone glycoside found in soy-based food products. Reported to reduce bone loss in overectomized rats.

Biochem/physiol Actions

Primary Target
A negative control for Genistein

Product does not compete with ATP.

Reversible: no

Cell permeable: no

Packaging

Packaged under inert gas

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 weeks at -20°C.

Other Notes

Uesugi, T., et al. 2001. Biol. Pharm. Bull.24, 368.
Kajiya, H., et al. 2000. J. Cell. Physiol.183, 83.
Hamakawa, T., et al. 1999. J. Neurosci. 19, 9306.
Wang, H., and Murphy, P.A. 1994. Agric. Food Chem. 42, 1666.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable