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341501

FeTMPyP

Catalyzes the isomerization of peroxynitrite (ONOO⁻) to nitrate (NO3⁻) under physiological conditions and at realistic dose-derived concentrations (kcat = 2.2 x 10⁶M⁻¹s⁻¹).

Synonym(e):

FeTMPyP, 5,10,15,20-Tetrakis(N-methyl-4ʹ-pyridyl)porphinato Iron (III) Chloride, Fe IIITMPyP(Cl)

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PackungsgrößeSKUVerfügbarkeitPreis
10 mg
Warenkorb auf Verfügbarkeit prüfen
€ 93,20

Über diesen Artikel

Empirische Formel (Hill-System):
C44H36Cl5FeN8
Molekulargewicht:
909.92
NACRES:
NA.77
UNSPSC Code:
12352200
Assay:
≥90% (TLC)
Form:
solid
Storage condition:
OK to freeze, desiccated (hygroscopic), protect from light

€ 93,20


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Quality Segment

assay

≥90% (TLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, desiccated (hygroscopic), protect from light

color

brown

solubility

water: 50 mg/mL

shipped in

ambient

storage temp.

−20°C

General description

Catalyzes the isomerization of peroxynitrite (ONOO) to nitrate (NO3) under physiological conditions and at realistic dose-derived concentrations (Kcat = 2.2 x 106 M-1s-1). Effectively prevents the oxidation of lipid components by peroxynitrite. Also catalytically decomposes superoxide radicals (O2·). Irradiation of the aqueous solution at 335 nm releases hydroxyl (OH·) radicals. FeTMPyP can also serve as a potential for drug detoxification of reactive oxygen species (ROS).

Biochem/physiol Actions

Cell permeable: no
Kcat = 2.2 x 106 M-1s-1 in catalyzing the isomerization of peroxynitrite (ONOO-) to nitrate (NO3-) under physiological conditions
Primary Target
Peroxynitrite (ONOO-)
Product does not compete with ATP.
Reversible: no

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 months at -20°C.

Other Notes

Lee, J., et al. 1998. J. Am. Chem. Soc. 120, 7493.
Hunt, J.A., et al. 1997. Chem. Biol. 4, 845.
Marla, S.S., et al. 1997. Proc. Natl. Acad. Sci. USA 94, 14243.
Stern, M.K., et al. 1996. J. Am. Chem. Soc. 118, 8735.
Faraggi, M., et al. 1984. Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med.46, 703.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

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Dieser Artikel
341492475872475870
form

solid

form

solid

form

solid

form

solid

assay

≥90% (TLC)

assay

≥95% (TLC)

assay

≥95% (TLC)

assay

≥95% (TLC)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

−20°C

solubility

water: 50 mg/mL

solubility

water: soluble

solubility

water: 1 mg/mL

solubility

aqueous base: soluble


Lagerklasse

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



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Verwandter Inhalt

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Global Trade Item Number

SKUGTIN
341501-10MG04055977215014

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