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07-823

Anti-phospho eIF4E (Ser209) Antibody

Upstate®, from rabbit

Synonym(e):

eukaryotic translation initiation factor 4E, CBP, EIF4EL1, EIF4F

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PackungsgrößeSKUVerfügbarkeitPreis
100 μL
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€ 340,00

Über diesen Artikel

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
polyclonal
Species reactivity:
human
Application:
WB
Citations:
19

€ 340,00


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biological source

rabbit

Quality Level

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human

species reactivity (predicted by homology)

rat (100% homologous), mouse (100% homologous), rabbit (100% homologous)

manufacturer/tradename

Upstate®

technique(s)

western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

phosphorylation (pSer209)

Gene Information

human ... EIF4E(1977)

General description

25 kDa

Immunogen

KLH conjugated synthetic peptide corresponding to amino acids surrounding Ser209 of human eIF4E. Sequence conserved in mouse and rat.

Application

Anti-phospho eIF4E (Ser209) Antibody is an antibody against phospho eIF4E (Ser209) for use in WB.
Research Category
Signaling
Research Sub Category
PI3K, Akt, & mTOR Signaling

RNA Binding Protein (RBP)

Biochem/physiol Actions

Recognizes eIF4E phosphorylated on Ser209.

Physical form

ImmunoAffinity Purified

Analysis Note

Routinely evaluated by immunoblot.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Dieser Artikel
MABS1865SAB5700437HPA019253
clone

polyclonal

clone

16D9.1, monoclonal

clone

polyclonal

clone

polyclonal

biological source

rabbit

biological source

mouse

biological source

rabbit

biological source

rabbit

species reactivity

human

species reactivity

human

species reactivity

mouse, human

species reactivity

human

antibody form

affinity isolated antibody

antibody form

purified immunoglobulin

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

shipped in

dry ice

shipped in

-

shipped in

wet ice

shipped in

wet ice

Gene Information

human ... EIF4E(1977)

Gene Information

human ... EIF4EBP2(1979)

Gene Information

human ... EIF4E(1977)

Gene Information

human ... EIF4E2(9470)


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Lagerklasse

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



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Verwandter Inhalt

All eukaryotic organisms require tight regulation of gene expression for complex processes such as development, differentiation, cell specification, and responses to environmental stimuli. Many genes are regulated post-transcriptionally, in addition to transcriptional mechanisms of gene regulation. RNA-binding proteins (RBPs) are essential for post-transcriptional gene regulation, linking transcription and translation in many processes including transcription, splicing, export, rate of translation and turnover. In all of these events, RBPs coordinate regulation of the amount of protein produced from mRNA transcripts.


Joanna Zuberek et al.
Biochemistry, 43(18), 5370-5379 (2004-05-05)
Eukaryotic translation initiation factor 4E (eIF4E) is essential for efficient protein synthesis in cap-dependent translation. The protein specifically binds the cap structure at the mRNA 5' terminus and facilitates the assembly of the mRNA with other initiation factors and the
Phosphorylation of eukaryotic initiation factor 4E (eIF4E) at Ser209 is not required for protein synthesis in vitro and in vivo
McKendrick, L, et al
European Journal of Biochemistry, 268, 5375-5385 (2001)
Modifications of eukaryotic initiation factor 4F (eIF4F) in adult cardiocytes by adenoviral gene transfer: differential effects on eIF4F activity and total protein synthesis rates
Saghir, A N, et al
The Biochemical Journal, 356, 557-566 (2001)



Global Trade Item Number

SKUGTIN
07-82304053252403798

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