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EIF4E

eukaryotic translation initiation factor 4E

Synonyms:
AUTS19, CBP, EIF4E1, EIF4EL1, EIF4F
Species:
Human EIF4E (1977), Mouse Eif4e (13684), Rat Eif4e (117045), domestic guinea pig Eif4e (100718596), cow EIF4E (281751), Domestic Rabbit EIF4E (100009338), sheep EIF4E (101112730), domestic cat EIF4E (101080377), dog EIF4E (487870), Thale Cress EIF4E (827529)
UniProtKB ID:
P06730, B7Z6V1, D6RCQ6, Q96E95
Gene ID:
  • Human(1977) Summary: The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of cellular mRNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the mRNA. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
  • Mouse(13684) eukaryotic translation initiation factor 4E
  • Rat(117045) eukaryotic translation initiation factor 4E
  • domestic guinea pig(100718596) eukaryotic translation initiation factor 4E
  • cow(281751) eukaryotic translation initiation factor 4E
  • Domestic Rabbit(100009338) eukaryotic translation initiation factor 4E
  • sheep(101112730) eukaryotic translation initiation factor 4E
  • domestic cat(101080377) eukaryotic translation initiation factor 4E
  • dog(487870) eukaryotic translation initiation factor 4E
  • Thale Cress(827529) translation initiation factor eIF-4E
  • chicken(422703) eukaryotic translation initiation factor 4E

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Antibodies

Product Number
Description
Species Reactivity
Application
ABE2695
Anti-eIF-4E, from rabbit, purified by affinity chromatography,
Species Reactivity
human, monkey, mouse, rat
Application
immunocytochemistry
western blot
SAB4300188
Anti-phospho-EIF4E (pSer209) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry
western blot
SAB4500735
Anti-EIF4E antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
SAB4504389
Anti-phospho-eIF4E (pSer209) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
SAB5700773
Anti-EIF4E antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot

Proteins

Product Number
Description
Species
SRP0255
eIF4E Active human, N-terminal GST-tag, recombinant, expressed in E. coli, ≥70% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
EMU195261
MISSION® esiRNA, targeting mouse Eif4e,
Species
mouse
EMU094691
MISSION® esiRNA, targeting mouse Eif4e,
Species
mouse