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Merck

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07-505

Anti-HDAC8 Antibody

serum, Upstate®

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Über diesen Artikel

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IP, WB
Citations:
7


biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human, mouse

manufacturer/tradename

Upstate®

technique(s)

immunoprecipitation (IP): suitable, western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... HDAC8(55869)

General description

48 kDa

Immunogen

GST fusion protein corresponding to amino acids 305-377 of human HDAC8

Application

Anti-HDAC8 Antibody is a Rabbit Polyclonal Antibody for detection of HDAC8 also known as histone deacetylase 8 & has been tested in IP & WB.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Histones

Biochem/physiol Actions

HDAC8

Physical form

30% glycerol
Antiserum

Preparation Note

2 years at -20°C

Analysis Note

routinely evaluated by immunoblot in in a nuclear extract of mouse liver

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Dieser Artikel
06-89005-100-I07-732
antibody form

serum

antibody form

purified antibody

antibody form

purified immunoglobulin

antibody form

purified antibody

biological source

rabbit

biological source

rabbit

biological source

mouse

biological source

rabbit

clone

polyclonal

clone

polyclonal

clone

2E10, monoclonal

clone

polyclonal

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

species reactivity

human, mouse

species reactivity

mouse, human, rat

species reactivity

mouse, human

species reactivity

human, mouse

shipped in

dry ice

shipped in

dry ice

shipped in

wet ice

shipped in

wet ice


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Lagerklasse

10 - Combustible liquids

wgk

WGK 1



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I Van den Wyngaert et al.
FEBS letters, 478(1-2), 77-83 (2000-08-03)
To date, seven different human histone deacetylases (HDACs) have been identified, which fall into two distinct classes. We have isolated and characterized a cDNA encoding a novel human HDAC, which we name HDAC8. HDAC8 shows a high degree of sequence
E Hu et al.
The Journal of biological chemistry, 275(20), 15254-15264 (2000-04-05)
Histone acetylation alters chromatin state by modifying lysines on histone and plays an important role in modulating gene transcription. A dynamic balance of histone acetylation/deacetylation is maintained by histone acetyltransferases and histone deacetylases. Emerging evidence suggests that a family of
J J Buggy et al.
The Biochemical journal, 350 Pt 1, 199-205 (2000-08-06)
Histone deacetylases (HDACs) are a growing family of enzymes implicated in transcriptional regulation by affecting the acetylation state of core histones in the nucleus of cells. HDACs are known to have key roles in the regulation of cell proliferation [Brehm



Global Trade Item Number

SKUGTIN
07-50504053252675492

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