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06-890

Sigma-Aldrich

Anti-HDAC3 Antibody

Upstate®, from rabbit

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

rabbit

Qualitätsniveau

Antikörperform

purified antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Speziesreaktivität

mouse, human, rat

Hersteller/Markenname

Upstate®

Methode(n)

western blot: suitable

Isotyp

IgG

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

dry ice

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... HDAC3(8841)

Spezifität

HDAC3

Immunogen

peptide corresponding to amino acids 411-428 of human HDAC3 (NEFYDGDHDNDKESDVEI)

Anwendung

Research Category
Epigenetik & nukleäre Funktionen
Research Sub Category
Histone
Anti-HDAC3 Antibody is a Rabbit Polyclonal Antibody for detection of HDAC3 also known as histone deacetylase 3 & has been tested in WB.

Qualität

routinely evaluated by immunoblot on a HeLa RIPA cell lysate

Zielbeschreibung

49kDa

Physikalische Form

Protein A chromatography
Format: Purified
of 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%

Lagerung und Haltbarkeit

2 years at -20°C

Rechtliche Hinweise

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1


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Die Dokumentenbibliothek aufrufen

Specific targeting and constitutive association of histone deacetylase complexes during transcriptional repression
Li, J., et al
Genes & Development, 16, 687-692 (2002)
Y Zeng et al.
The Journal of biological chemistry, 273(44), 28921-28930 (1998-10-24)
Histone deacetylase-2 (HDAC2) is a component of a complex that mediates transcriptional repression in mammalian cells. A mouse HDAC2 cDNA was used to identify several recombinant clones containing the entire mouse HDAC2 gene. The mouse HDAC2 gene spans over 36
Histone acetylation and transcriptional regulatory mechanisms.
Struhl, K
Genes & Development, 12, 599-606 (1998)
K Nakade et al.
Cell death and differentiation, 14(8), 1398-1405 (2007-04-28)
Among the events that control cellular differentiation, the acetylation of histones plays a critical role in the regulation of transcription and the modification of chromatin. Jun dimerization protein 2 (JDP2), a member of the AP-1 family, is an inhibitor of
Histone deacetylase 3 is required for maintenance of bone mass during aging.
McGee-Lawrence, ME; Bradley, EW; Dudakovic, A; Carlson, SW; Ryan, ZC; Kumar, R; Dadsetan et al.
Bone null

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