06-937
Anti-phospho-STAT6 (Tyr641) Antibody
Upstate®, from rabbit
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100 μL
€ 461,00
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100 μL
€ 461,00
About This Item
UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Empfohlene Produkte
Biologische Quelle
rabbit
Qualitätsniveau
Antikörperform
purified antibody
Antikörper-Produkttyp
primary antibodies
Klon
polyclonal
Speziesreaktivität
human, mouse
Hersteller/Markenname
Upstate®
Methode(n)
western blot: suitable
Isotyp
IgG
NCBI-Hinterlegungsnummer
UniProt-Hinterlegungsnummer
Versandbedingung
wet ice
Posttranslationale Modifikation Target
phosphorylation (pTyr641)
Angaben zum Gen
human ... STAT6(6778)
Spezifität
phospho-STAT6
Immunogen
peptide corresponding to amino acids 631-645 of human STAT6 (C-PEQMGKDGRGpYVPAT)
Anwendung
Research Category
Epigenetik & nukleäre Funktionen
Epigenetik & nukleäre Funktionen
Research Sub Category
Transkriptionsfaktoren
Transkriptionsfaktoren
This Anti-phospho-STAT6 (Tyr641) Antibody is validated for use in WB for the detection of phospho-STAT6 (Tyr641).
Qualität
routinely evaluated by immunoblot on lysates of HepG2 cells, serum starved, then stimulated with IL-4
Zielbeschreibung
100kDa
Physikalische Form
Protein A purified
0.1M Tris-Glycine, 0.15M NaCl, 0.05% Sodium Azide, pH 7.4.
Format: Purified
Lagerung und Haltbarkeit
Maintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt.
Rechtliche Hinweise
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Haftungsausschluss
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Lagerklassenschlüssel
12 - Non Combustible Liquids
WGK
WGK 1
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Analysenzertifikate (COA)
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F W Quelle et al.
Molecular and cellular biology, 15(6), 3336-3343 (1995-06-01)
By searching a database of expressed sequences, we identified a member of the signal transducers and activators of transcription (Stat) family of proteins. Human and murine full-length cDNA clones were obtained and sequenced. The sequence of the human cDNA was
Giulia Veltri et al.
Cancers, 13(15) (2021-08-08)
Lymphoblastic lymphoma (LBL) is the second most common type of non-Hodgkin lymphoma in childhood, mainly of T cell origin (T-LBL). Although current treatment protocols allow a complete remission in 85% of cases, the second-line treatment overall survival for patients with
Defective GATA-3 expression in Th2 LCR-deficient mice.
Soo Seok Hwang,Kiwan Kim,Gap Ryol Lee
Biochemical and biophysical research communications null
Tetsuya Kubota et al.
Nature communications, 9(1), 4863-4863 (2018-11-20)
M2a-subtype macrophage activation is known to be impaired in obesity, although the underlying mechanisms remain poorly understood. Herein, we demonstrate that, the IL-4/Irs2/Akt pathway is selectively impaired, along with decreased macrophage Irs2 expression, although IL-4/STAT6 pathway is maintained. Indeed, myeloid
Jason C O'Connor et al.
Journal of immunology (Baltimore, Md. : 1950), 178(11), 6886-6893 (2007-05-22)
Chronic elevation of proinflammatory markers in type 2 diabetes (T2D) is well defined, but the role of anti-inflammatory cytokines in T2D is less clear. In this study, we report that normal IL-4-dependent elaboration of IL-1 receptor antagonist (IL-1RA) requires IRS-2-mediated
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