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05-577

Anti-PP2A Antibody, C subunit, demethylated, clone 4b7

ascites fluid, clone 4b7, Upstate®

Synonym(e):

Anti-NEDLBA, Anti-PP2Ac, Anti-PP2CA, Anti-PP2Calpha, Anti-RP-C

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PackungsgrößeSKUVerfügbarkeitPreis
200 μL
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€ 416,00

Über diesen Artikel

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
4b7, monoclonal
Application:
ICC, IP, WB
Citations:
20

€ 416,00


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biological source

mouse

Quality Level

conjugate

unconjugated

antibody form

ascites fluid

antibody product type

primary antibodies

clone

4b7, monoclonal

species reactivity

vertebrates

manufacturer/tradename

Upstate®

technique(s)

immunocytochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... PPP2CA(5515)

General description

36kDa

Immunogen

peptide (C-RGEPHVTRRTPDYFL) corresponding to amino acids 295-309 of human PP2A, C subunit

Application

Anti-PP2A Antibody, C subunit, demethylated, clone 4b7 is an antibody against PP2A for use in IC, IP & WB.
Research Category
Signaling

Neuroscience
Research Sub Category
Kinases & Phosphatases

Neurodegenerative Diseases

Biochem/physiol Actions

unmethylated PP2A, C subunit

Physical form

0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
Ascites

Preparation Note

2 years at -20°C

Analysis Note

Control
Positive Antigen Control: Catalog #12-301, non-stimulated A431 cell lysate. Add 2.5µL of 2-mercaptoethanol/100µL of lysate and boil for 5 minutes to reduce the preparation. Load 20µg of reduced lysate per lane for minigels.
routinely evaluated by immunoblot on RIPA lysates from A431 cells

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Dieser Artikel
05-54507-32407-250
antibody form

ascites fluid

antibody form

culture supernatant

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

clone

4b7, monoclonal

clone

7A6, monoclonal

clone

polyclonal

clone

polyclonal

species reactivity

vertebrates

species reactivity

mouse, Saccharomyces cerevisiae, human

species reactivity

bovine, rat, human, mouse

species reactivity

human, mouse, Xenopus, pig, rat

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

biological source

mouse

biological source

mouse

biological source

rabbit

biological source

rabbit

Gene Information

human ... PPP2CA(5515)

Gene Information

human ... PPP2CA(5515)

Gene Information

human ... PPP2CA(5515)

Gene Information

human ... PPP2R1A(5518)


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Lagerklasse

10 - Combustible liquids

wgk

WGK 1



Analysenzertifikate (COA)

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Xiaoyu Xia et al.
Cell cycle (Georgetown, Tex.), 14(12), 1938-1947 (2015-04-04)
Leucine carboxyl methyltransferase-1 (LCMT1) and protein phosphatase methylesterase-1 (PME-1) are essential enzymes that regulate the methylation of the protein phosphatase 2A catalytic subunit (PP2AC). LCMT1 and PME-1 have been linked to the regulation of cell growth and proliferation, but the
Juyeon Hwang et al.
The Journal of biological chemistry, 291(40), 21008-21019 (2016-08-11)
The protein phosphatase 2A (PP2A) subfamily of phosphatases, PP2A, PP4, and PP6, are multifunctional serine/threonine protein phosphatases involved in many cellular processes. Carboxyl methylation of the PP2A catalytic subunit (PP2Ac) C-terminal leucine is regulated by the opposing activities of leucine
Ying Zhou et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 34(12), 16414-16431 (2020-10-19)
Polyphyllin I (PPI) is a natural phytochemical drug isolated from plants which can inhibit the proliferation of cancer cells. One of the PPI tumor-inhibitory effects is through downregulating the expression of Cancerous Inhibitor of PP2A (CIP2A), the latter, is found



Global Trade Item Number

SKUGTIN
05-57704053252339370

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