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1598201

USP

Raloxifen -hydrochlorid

United States Pharmacopeia (USP) Reference Standard

Synonym(e):

Keoxifen -hydrochlorid, LY 156758, [6-Hydroxy-2-(4-hydroxyphenyl)-benzo[b]thien-3-yl][4-[2-(1-piperidinyl)-ethoxy]-phenyl]-methanon -hydrochlorid

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PackungsgrößeSKUVerfügbarkeitPreis
200 mg
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€ 407,00

Über diesen Artikel

Empirische Formel (Hill-System):
C28H27NO4S · HCl
CAS-Nummer:
Molekulargewicht:
510.04
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:

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grade

pharmaceutical primary standard

API family

raloxifene

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

Cl[H].Oc1ccc(cc1)-c2sc3cc(O)ccc3c2C(=O)c4ccc(OCCN5CCCCC5)cc4

InChI

1S/C28H27NO4S.ClH/c30-21-8-4-20(5-9-21)28-26(24-13-10-22(31)18-25(24)34-28)27(32)19-6-11-23(12-7-19)33-17-16-29-14-2-1-3-15-29;/h4-13,18,30-31H,1-3,14-17H2;1H

InChI key

BKXVVCILCIUCLG-UHFFFAOYSA-N

Gene Information

human ... ESR2(2100)

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Raloxifene hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Raloxifene Hydrochloride Tablets

Biochem/physiol Actions

Raloxifen ist ein selektiver Östrogenrezeptor-Modulator (SERM), es wirkt wie ein Anti-Östrogen in sowohl Brust- als auch Gebärmutter-Gewebe, während es östrogen in Knochen ist. Könnte gegen Östrogen-sensitive Tumore wirksam sein.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

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Dieser Artikel
Y0001134PHR1852R1402
manufacturer/tradename

USP

manufacturer/tradename

EDQM

manufacturer/tradename

-

manufacturer/tradename

-

grade

pharmaceutical primary standard

grade

pharmaceutical primary standard

grade

certified reference material, pharmaceutical secondary standard

grade

-

format

neat

format

neat

format

neat

format

-

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical

application(s)

-

Gene Information

human ... ESR2(2100)

Gene Information

human ... ESR2(2100)

Gene Information

human ... ESR2(2100)

Gene Information

human ... ESR2(2100)

API family

raloxifene

API family

raloxifene

API family

raloxifene

API family

-


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pictograms

Health hazard

signalword

Warning

Hazard Classifications

Carc. 2 - Repr. 2

Lagerklasse

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable



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Analysenzertifikate (COA)

Lot/Batch Number

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Tuan Hiep Tran et al.
Journal of nanoscience and nanotechnology, 14(7), 4820-4831 (2014-04-25)
The main aim of this study was to improve the oral bioavailability of raloxifene (RXF), a selective estrogen receptor modulator, by incorporation into solid lipid nanoparticles (SLN). RXF-loaded SLN was prepared by homogenization-sonication technique and characterized through physicochemical, pharmacokinetic, and
K R Snyder et al.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 57(18), 1669-1675 (2000-09-28)
The pharmacology, pharmacokinetics, clinical efficacy, adverse effects, and therapeutic role of raloxifene hydrochloride are reviewed. Raloxifene is a selective estrogen-receptor modulator (SERM) that has been approved for use in the prevention and treatment of osteoporosis in postmenopausal women. A SERM
[Raloxifene hydrochloride (Evista Tablet 60 mg) for postmenopausal osteoporosis: mode of action and clinical efficacy].
Hiroyuki Kobayashi et al.
Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 125(1), 37-48 (2005-03-02)



Global Trade Item Number

SKUGTIN
1598201-200MG04061833854358

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