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Z0292

Sigma-Aldrich

α-Zearalanol

~98% (HPLC), powder, mycotoxin

Synonym(e):

2,4-Dihydroxy-6-(6α,10-dihydroxyundecyl)benzoic acid μ-lactone

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About This Item

Empirische Formel (Hill-System):
C18H26O5
CAS-Nummer:
26538-44-3
Molekulargewicht:
322.40
EG-Nummer:
247-769-0
MDL-Nummer:
MFCD00083519
UNSPSC-Code:
12352200
PubChem Substanz-ID:
24902163
NACRES:
NA.77

product name

α-Zearalanol, ~98% (HPLC)

Biologische Quelle

synthetic (organic)

Qualitätsniveau

200

Sterilität

non-sterile

Assay

~98% (HPLC)

Form

powder

Arzneimittelkontrolle

regulated under CDSA - not available from Sigma-Aldrich Canada

Methode(n)

UHPLC: suitable

Löslichkeit

methanol: 1.96-2.04 mg/mL, clear, colorless to faintly yellow

Versandbedingung

ambient

Lagertemp.

−20°C

SMILES String

C[C@H]1CCC[C@H](O)CCCCCc2cc(O)cc(O)c2C(=O)O1

InChI

1S/C18H26O5/c1-12-6-5-9-14(19)8-4-2-3-7-13-10-15(20)11-16(21)17(13)18(22)23-12/h10-12,14,19-21H,2-9H2,1H3/t12-,14+/m0/s1

InChIKey

DWTTZBARDOXEAM-GXTWGEPZSA-N

Verwandte Kategorien

Piktogramme

Health hazardCorrosion
GHS08,GHS05

Signalwort

Danger

H-Sätze

H314,H361d

Gefahreneinstufungen

Repr. 2 - Skin Corr. 1B

Lagerklassenschlüssel

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

Analysenzertifikate (COA)

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C Mastri et al.
Journal of steroid biochemistry, 23(3), 279-289 (1985-09-01)
It is now well established that the mycotoxin zearalenone and some of its derivatives possess oestrogenic activity. In the present study, the binding characteristics of [3H]zearalanol (P-1496) to different classes of sites including [1] the oestrogen receptor, [2] the higher
Yilong Dong et al.
European journal of pharmacology, 670(2-3), 392-398 (2011-09-29)
Although favorable effects of estrogen replacement therapy on Alzheimer's disease on postmenopausal women have been recognized, an associated increased incidence of uterine and breast tumors has jeopardized the clinical use of estrogen. Phytoestrogen α-zearalanol (α-ZAL) is a reductive product of
Han-Yun Hsieh et al.
Journal of the science of food and agriculture, 92(6), 1230-1237 (2011-10-21)
Zeranol (Z) is a semi-synthetic mycotoxin that is used in some countries as a growth-promoting agent in livestock. In view of the known oestrogenic actions by Z and certain Z analogues, significant concerns exist with regard to the presence of
Hongfeng Wang et al.
The Journal of reproduction and development, 58(3), 338-343 (2012-03-27)
Alpha-Zearalenol (α-ZEA) is one of derivatives from Zearalenone (ZEA) which impacts mammalian reproduction and development. Previous studies have shown that pigs are sensitive to the estradiol-like effects of α-ZEA. However, the effect of α-ZEA for the early embryonic development has
Mario Thevis et al.
Drug testing and analysis, 3(11-12), 777-783 (2011-11-19)
Zeranol ((7R,11S)-7,15,17-trihydroxy-11-methyl-12-oxabicyclo[12.4.0]octadeca-1(14),15,17-trien-13-one, also referred to as 7α-zearalanol, Ralone®, Frideron®, Ralgro®, etc.) is a semi-synthetic estrogenic veterinary drug with growth-promoting properties. Its use regarding animal husbandry has been prohibited in the European Union since 1981 and, due to its anabolic effects
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