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V1255
D-Valin
BioReagent, suitable for cell culture
Synonym(e):
(R)-α-Aminoisovaleriansäure, (R)-2-Amino-3-methylbuttersäure
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| Packungsgröße | SKU | Verfügbarkeit | Preis |
|---|---|---|---|
| 1 g | Warenkorb auf Verfügbarkeit prüfen | € 26,10 € 22,18 | |
| 5 g | Warenkorb auf Verfügbarkeit prüfen | € 90,20 € 76,67 | |
| 25 g | Warenkorb auf Verfügbarkeit prüfen | € 322,00 |
Über diesen Artikel
Lineare Formel:
(CH3)2CHCH(NH2)CO2H
CAS-Nummer:
Molekulargewicht:
117.15
UNSPSC Code:
12352209
NACRES:
NA.75
PubChem Substance ID:
EC Number:
211-368-9
Beilstein/REAXYS Number:
1721135
MDL number:
€ 22,18
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Technischer Dienst
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Unterstützung erhaltenbiological source
synthetic (organic)
Quality Segment
product line
BioReagent
form
powder
technique(s)
cell culture | mammalian: suitable
mp
>295 °C (subl.) (lit.)
shipped in
ambient
storage temp.
room temp
SMILES string
CC(C)[C@@H](N)C(O)=O
InChI
1S/C5H11NO2/c1-3(2)4(6)5(7)8/h3-4H,6H2,1-2H3,(H,7,8)/t4-/m1/s1
InChI key
KZSNJWFQEVHDMF-SCSAIBSYSA-N
General description
L-Valine is an essential non-polar amino acid. D-Valine is the non-proteinogenic isomer of valine.
Application
D-Valine has been used as a supplement in:
- Dulbecco′s modified Eagle′s medium (DMEM)/Nutrient Mixture F-12 Ham (F-12) for mice renal proximal tubule cell (RPTC) culture[1]
- endothelial cell growth medium MV2 for rat lung microvascular endothelial cell (RLMEC) culture[2]
- DMEM/F-12 for mouse tracheal epithelial cell (MTEC) culture[3]
Biochem/physiol Actions
D-Valine has a broad range of industrial applications such as semi-synthetic veterinary antibiotics, pharmaceutical drugs, and agricultural pesticides.[4]
D-valine is used in cell culture as a selective inhibitor of cell proliferation, wherein it inhibits cells that lack the enzyme D-amino acid oxidase. Historically D-valine has been used to inhibit fibroblast growth while allowing selective growth of epithelial cells.
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Dieser Artikel | |||
|---|---|---|---|
| technique(s) cell culture | mammalian: suitable | technique(s) - | technique(s) - | technique(s) cell culture | mammalian: suitable |
| form powder | form - | form powder | form powder |
| biological source synthetic (organic) | biological source synthetic | biological source - | biological source non-animal source |
| storage temp. room temp | storage temp. - | storage temp. - | storage temp. 2-30°C |
| shipped in ambient | shipped in - | shipped in - | shipped in - |
| Quality Level 200 | Quality Level 300, 400 | Quality Level 200 | Quality Level 400 |
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Lagerklasse
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Verwandter Inhalt
S F Gilbert et al.
Cell, 5(1), 11-17 (1975-05-01)
A nutrient medium has been developed to enable the growth of normal epithelial cells while selectively inhibiting fibroblast proliferation. In this medium, D-valine is substituted for L-valine; and only those cells containing D-amino acid oxidase can convert the D-amino acid
Ming Chen et al.
World journal of microbiology & biotechnology, 32(10), 171-171 (2016-08-28)
D-Valine is an important organic chiral source and has extensive industrial application, which is used as intermediate for the synthesis of agricultural pesticides, semi-synthetic veterinary antibiotics and pharmaceutical drugs. Its derivatives have shown great activity in clinical use, such as
Hui Li et al.
PLoS pathogens, 14(1), e1006821-e1006821 (2018-01-05)
The highly pathogenic avian influenza (HPAI) H5N1 influenza virus has been a public health concern for more than a decade because of its frequent zoonoses and the high case fatality rate associated with human infections. Severe disease following H5N1 influenza
Global Trade Item Number
| SKU | GTIN |
|---|---|
| V1255-1G | 04061837429156 |
| V1255-25G | 04061837429163 |
| V1255-5G | 04061837429170 |