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U9507
Urocortin II mouse
Synonym(e):
UCN-II
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| Packungsgröße | SKU | Verfügbarkeit | Preis |
|---|---|---|---|
| 500 μg | Warenkorb auf Verfügbarkeit prüfen | € 422,00 |
Über diesen Artikel
Form:
solid
Assay:
≥97% (HPLC)
Biological source:
mouse
Technischer Dienst
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Unterstützung erhaltenbiological source
mouse
Quality Level
assay
≥97% (HPLC)
form
solid
technique(s)
immunohistochemistry: suitable
UniProt accession no.
storage temp.
−20°C
Gene Information
mouse ... Ucn2(171530)
Application
Mouse urocortin II can be used for immunohistochemistry.[1]
Biochem/physiol Actions
Urocortin II is a CRF-related neuropeptide having high affinity for CRF2 receptor. It stimulates protein kinase A through CRF2 receptor and increases the contractility in rabbit ventricular myocytes.[2] It also facilitates pro-inflammatory effects in human intestinal cells through corticotropin-releasing hormone receptor 2α.[3]
corticotropin-releasing factor (CRF) peptide
Other Notes
Lyophilized from 0.1% TFA in H2O
1 of 1
Dieser Artikel | |||
|---|---|---|---|
| technique(s) immunohistochemistry: suitable | technique(s) ligand binding assay: suitable | technique(s) - | technique(s) immunohistochemistry: 1:50-1:100 |
| assay ≥97% (HPLC) | assay ≥97% (HPLC) | assay >97% (SDS-PAGE) | assay - |
| biological source mouse | biological source human | biological source mouse | biological source rabbit |
| form solid | form solid | form lyophilized powder | form buffered aqueous solution |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
| Gene Information mouse ... Ucn2(171530) | Gene Information human ... UCN3(114131) | Gene Information mouse ... IGF2(16002), Igf2(16002) | Gene Information human ... UCN(7349) |
Lagerklasse
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Alan C Moss et al.
Gut, 56(9), 1210-1217 (2007-04-07)
Urocortin II (UcnII) is a neuropeptide that binds with high affinity to the corticotropin-releasing hormone receptor 2 (CRHR2) in peripheral tissues. UcnII is synthesised in the intestine, but its role in human intestinal inflammation is largely unknown. Responses of human
David P Burns et al.
The Journal of physiology, 596(21), 5175-5197 (2018-08-31)
Impaired ventilatory capacity and diaphragm muscle weakness are prominent features of Duchenne muscular dystrophy, with strong evidence of attendant systemic and muscle inflammation. We performed a 2-week intervention in young wild-type and mdx mice, consisting of either injection of saline
Li-Zhen Yang et al.
Cardiovascular research, 69(2), 402-411 (2006-01-03)
Urocortin II (UcnII), a peptide of the corticotropin-releasing factor (CRF) family, exerts profound actions on the cardiovascular system. Direct effects of UcnII on adult cardiomyocytes have not been evaluated before. Our aim was to characterize functional effects of UcnII on
Global Trade Item Number
| SKU | GTIN |
|---|---|
| U9507-500UG | 04061832678122 |