T1698

Tetradecylthioacetic acid

≥97% (NMR)

• Synonym(e): TTA
• Lineare Formel: C₁₄H₂₉-S-CH₂COOH
• CAS-Nummer: 2921-20-2
• Molekulargewicht: 288.49
• NACRES: NA.77
• PubChem Substance ID: 24278726
• UNSPSC Code: 12352200
• MDL number: MFCD00128230
• Assay: ≥97% (NMR)
• Quality level: 100

Eigenschaften

• Quality Level: 100
• assay: ≥97% (NMR)
• color: white
• solubility: DMSO: soluble ≥22 mg/mL
• SMILES string: CCCCCCCCCCCCCCSCC(O)=O
• InChI: 1S/C16H32O2S/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-19-15-16(17)18/h2-15H2,1H3,(H,17,18)
• InChI key: IPBCWPPBAWQYOO-UHFFFAOYSA-N
• Gene Information: human ... PPARA(5465)

Beschreibung

Biochem/physiol Actions

PPARα agonist; activation in ranking order: PPARδ > PPARα > PPARγ

Tetradecylthioacetic acid (TTA) is known to modulate lipid homeostasis. TTA can increase fatty acid oxidation and ketogenesis, which can subsequently prevent adiposity and insulin resistance[1]. Furthermore, TTA can enhance cardiac functions during experimental heart failure[2].

Features and Benefits

This compound is featured on the Nuclear Receptors (PPARs) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Packaging

Packaged under nitrogen.

Preparation Note

Tetradecylthioacetic acid is soluble in DMSO at a concentration that is greater than or equal to 22 mg/ml.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)