PPARA
peroxisome proliferator-activated receptor alpha
Synonyms:
NR1C1, PPAR, PPARalpha, hPPAR
Species:
Human PPARA (5465), Mouse Ppara (19013), Rat Ppara (25747), domestic guinea pig Ppara (100135604), chicken PPARA (374120), naked mole-rat Ppara (101725514), Domestic Rabbit PPARA (100009308), Goat PPARA (100861393), sheep PPARA (100190976), dog PPARA (403654) ...More
UniProtKB ID:
Gene ID:
- Human(5465) Summary: Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined. [provided by RefSeq, Jul 2008]
- Mouse(19013) peroxisome proliferator activated receptor alpha
- Rat(25747) peroxisome proliferator activated receptor alpha
- domestic guinea pig(100135604) peroxisome proliferator activated receptor alpha
- chicken(374120) peroxisome proliferator-activated receptor alpha
- naked mole-rat(101725514) peroxisome proliferator-activated receptor alpha
- Domestic Rabbit(100009308) peroxisome proliferator-activated receptor alpha
- Goat(100861393) peroxisome proliferator-activated receptor alpha
- sheep(100190976) peroxisome proliferator-activated receptor alpha
- dog(403654) peroxisome proliferator-activated receptor alpha
- Horse(100049840) peroxisome proliferator-activated receptor alpha
- domestic cat(101095837) peroxisome proliferator-activated receptor alpha
- domestic cat(100049013) peroxisome proliferator-activated receptor alpha
- cow(281992) peroxisome proliferator-activated receptor alpha
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Small Molecule - Activator
Small Molecule - Agonist
Product Number
Description
Species
Fenofibrate Related Compound B, United States Pharmacopeia (USP) Reference Standard,
Species
human
Small Molecule - Antagonist
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PPARA, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, goat, guinea pig, horse, human, rabbit
Application
western blot
Monoclonal Anti-PPARA antibody produced in mouse, clone 1A8, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
immunofluorescence
Anti-PPAR-α antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-PPARA antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
human
Application
western blot
Anti-PPARA antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
western blot
western blot
Proteins
Product Number
Description
Species
PPARα, ligand binding domain (170-468) human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Species
human
PPARα isotype, ligand binding domain, GST tagged human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Species
human
PPARα isotype, GST tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE),
Species
human
esiRNA
Product Number
Description
Species