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T0201
Tau-381 human
recombinant, expressed in E. coli, ≥90% (SDS-PAGE), lyophilized powder
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| Packungsgröße | SKU | Verfügbarkeit | Preis |
|---|---|---|---|
| 50 μg | Warenkorb auf Verfügbarkeit prüfen | € 608,00 |
Über diesen Artikel
Form:
lyophilized powder
Assay:
≥90% (SDS-PAGE)
Biological source:
human
Recombinant:
expressed in E. coli
Mol wt:
39.7 kDa
€ 608,00
Warenkorb auf Verfügbarkeit prüfen
Technischer Dienst
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Unterstützung erhaltenbiological source
human
Quality Level
recombinant
expressed in E. coli
assay
≥90% (SDS-PAGE)
form
lyophilized powder
mol wt
39.7 kDa
UniProt accession no.
application(s)
cell analysis
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... MAPT(4137)
General description
The gene microtubule associated protein tau (MAPT) is localized on human chromosome 17q21.3. It is expressed in neurons, more specifically in axons.
Biochem/physiol Actions
Isoform of Tau, variant 1N3R, having 3 microtubule binding repeats (R) and one amino terminal insert (N).
Microtubule associated protein tau (MAPT) aids in the assembly and maintenance of microtubule structure. Loss of expression of MAPT results in developmental delay and learning disability. The protein has been associated with pathology of Alzheimer′s disease (AD).
Preparation Note
Lyophilized from MES, pH 6.8, containing NaCl and EGTA. When reconstituted in water to a protein concentration of 1 mg/mL, the resulting buffer will have ~50 mM MES, pH 6.8, 100 mM NaCl, and 0.5 mM EGTA.
1 of 1
Dieser Artikel | |||
|---|---|---|---|
| assay ≥90% (SDS-PAGE) | assay ≥90% (SDS-PAGE) | assay ≥90% (SDS-PAGE) | assay ≥90% (SDS-PAGE) |
| recombinant expressed in E. coli | recombinant expressed in E. coli | recombinant expressed in E. coli | recombinant expressed in E. coli |
| biological source human | biological source human | biological source human | biological source human |
| form lyophilized powder | form lyophilized powder | form lyophilized powder | form lyophilized powder |
| mol wt 39.7 kDa | mol wt 40 kDa | mol wt 36.8 kDa | mol wt 45.9 kDa |
| Gene Information human ... MAPT(4137) | Gene Information human ... MAPT(4137) | Gene Information human ... MAPT(4137) | Gene Information human ... MAPT(4137) |
Lagerklasse
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Verwandter Inhalt
Product Information Sheet
Microdeletion encompassing MAPT at chromosome 17q21. 3 is associated with developmental delay and learning disability
Shaw-Smith, Charles, et al
Nature Genetics (2006)
The H1c haplotype at the MAPT locus is associated with Alzheimer's disease
A.J. Myers
Human Molecular Genetics (2005)
Jesus Avila et al.
Physiological reviews, 84(2), 361-384 (2004-03-27)
The morphology of a neuron is determined by its cytoskeletal scaffolding. Thus proteins that associate with the principal cytoskeletal components such as the microtubules have a strong influence on both the morphology and physiology of neurons. Tau is a microtubule-associated
Global Trade Item Number
| SKU | GTIN |
|---|---|
| T0201-50UG | 04061833385494 |