SML2722

MU140

≥98% (HPLC)

• Synonym(e): 1-Methyl-4-(9-(2-phenyl-phenyl)-7-oxa-2-aza-bicyclo[4.3.0]nona-1,3,5,8-tetraen-3-yl)-1H-pyrazole, 3-(Biphenyl-2-yl)-5-(1-methyl-1H-pyrazol-4-yl)furo[3,2-b]pyridine, 3-[1,1′-Biphenyl]-2-yl-5-(1-methyl-1H-pyrazol-4-yl)-furo[3,2-b]pyridine, MU1210 inactive control, MU1210 negative control, VN270, VN339 inactive control, VN339 negative control
• Empirische Formel (Hill-System): C₂₃H₁₇N₃O
• CAS-Nummer: 1821205-76-8
• Molekulargewicht: 351.40
• UNSPSC Code: 41121813
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: powder

Eigenschaften

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: −20°C
• SMILES string: CN(N=C1)C=C1C2=CC=C(OC=C3C4=C(C5=CC=CC=C5)C=CC=C4)C3=N2
• InChI key: QSBNKGGRYOLZND-UHFFFAOYSA-N

Beschreibung

Biochem/physiol Actions

Inactive (negative) control for the cdc-like kinase (cdc2-like kinase) CLK1, CLK2, CLK4, and homeodomain-interacting protein kinase 2 (HIPK2) inhibitor MU1210.

MU140 is a structure analog of and the recommended inactive (negative) control for MU1210, an inhibitor against cdc-like kinase (cdc2-like kinase) CLK1, CLK2, CLK4, and homeodomain-interacting protein kinase 2 (HIPK2). MU140 exhibits no inhbitory potency toward CLK1/2/3/4, DYRK1a/1b/2 or HIPK1/2/3 (IC₅₀ >3 μM).

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable