SML0905

Dimethylenastron

≥98% (HPLC)

• Synonym(e): 2,3,4,6,7,8-Hexahydro-4-(3-hydroxyphenyl)-7,7-dimethyl-2-thioxo-5(1H)-quinazolinone
• Empirische Formel (Hill-System): C₁₆H₁₈N₂O₂S
• CAS-Nummer: 863774-58-7
• Molekulargewicht: 302.39
• UNSPSC Code: 12352200
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: powder

Eigenschaften

• InChI: 1S/C16H18N2O2S/c1-16(2)7-11-13(12(20)8-16)14(18-15(21)17-11)9-4-3-5-10(19)6-9/h3-6,14,19H,7-8H2,1-2H3,(H2,17,18,21)
• InChI key: RUOOPLOUUAYNPY-UHFFFAOYSA-N
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 15 mg/mL, clear
• storage temp.: 2-8°C

Beschreibung

Biochem/physiol Actions

Dimethylenastron is specific, reversible inhibitor of the mitotic motor kinesin Eg5.

Dimethylenastron is specific, reversible inhibitor of the mitotic motor kinesin Eg5. Dimethylenastron inhibits bipolar spindle formation, and inhibits proliferation, migration and invasion of several pancreatic cancer cell lines in cell based assays.

Features and Benefits

This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Sicherheitshinweise

• Lagerklasse: 13 - Non Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable