SML0905

Dimethylenastron

≥98% (HPLC)

• Synonym(e): 2,3,4,6,7,8-Hexahydro-4-(3-hydroxyphenyl)-7,7-dimethyl-2-thioxo-5(1H)-quinazolinone
• Empirische Formel (Hill-System): C₁₆H₁₈N₂O₂S
• CAS-Nummer: 863774-58-7
• Molekulargewicht: 302.39
• UNSPSC Code: 12352200
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: powder

Eigenschaften

• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 15 mg/mL, clear
• storage temp.: 2-8°C
• InChI: 1S/C16H18N2O2S/c1-16(2)7-11-13(12(20)8-16)14(18-15(21)17-11)9-4-3-5-10(19)6-9/h3-6,14,19H,7-8H2,1-2H3,(H2,17,18,21)
• InChI key: RUOOPLOUUAYNPY-UHFFFAOYSA-N

Beschreibung

Biochem/physiol Actions

Dimethylenastron is specific, reversible inhibitor of the mitotic motor kinesin Eg5.

Dimethylenastron is specific, reversible inhibitor of the mitotic motor kinesin Eg5. Dimethylenastron inhibits bipolar spindle formation, and inhibits proliferation, migration and invasion of several pancreatic cancer cell lines in cell based assays.

Features and Benefits

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Sicherheitshinweise

• Lagerklasse: 13 - Non Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable