The stability of this product in solution has not been determined. The solubility of this material is tested at 50 mg/mL. Other sources report that this compound is also soluble at 100 mg/mL in DMSO. In addition, prepared solutions are stable for 1 month at -20°C and 6 months at -80°C. This information has not been validated.
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S0375
D-Saccharinsäure 1,4-Lacton Monohydrat
≥98.0% (HPLC)
Synonym(e):
D-Glucarsäure-1,4-lacton, D-Saccharolacton
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Über diesen Artikel
Empirische Formel (Hill-System):
C6H8O7 · H2O
CAS-Nummer:
Molekulargewicht:
210.14
UNSPSC Code:
12352201
NACRES:
NA.25
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
85594
Preise und Verfügbarkeit sind derzeit nicht verfügbar.
Technischer Dienst
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Unterstützung erhaltenQuality Segment
assay
≥98.0% (HPLC)
form
powder
impurities
≤10.0% water (Karl Fischer)
color
white
mp
91 - 93 °C ((196 - 199 °F ))
solubility
water: 50 mg/mL, clear, colorless to faintly yellow
storage temp.
2-8°C
SMILES string
O.O[C@@H]1[C@@H](O)C(=O)O[C@@H]1[C@H](O)C(O)=O
InChI
1S/C6H8O7.H2O/c7-1-2(8)6(12)13-4(1)3(9)5(10)11;/h1-4,7-9H,(H,10,11);1H2/t1-,2-,3+,4+;/m1./s1
InChI key
NPFKVZHSFSFLPU-QGBSHYGGSA-N
General description
D-Saccharic acid 1,4-lactone monohydrate (DSAL) has an ability to inhibit the activity of β-glucuronidase enzyme.It also potentially inhibits Klotho deglycosylation of excitatory amino acid transporters (EAATs) and peptide transporters (PEPTs).
Application
D-Saccharic acid 1,4-lactone monohydrate has been used as a constituent of phosphate buffer to block incidental β-glucuronidase activity in Streptococcus pneumoniae hyaluronan lyase (SpnHL) activity assay. It has also been used as a component of reaction mixture in Iduronidase activity assay and UDP-glucuronosyltransferase 1 (UGT1A1) inhibition assay.
Other Notes
To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.
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Dieser Artikel | |||
|---|---|---|---|
| assay ≥98.0% (HPLC) | assay ≥99% | assay - | assay ≥99.0% (GC) |
| solubility water: 50 mg/mL, clear, colorless to faintly yellow | solubility water: soluble 25 mg/mL, clear, colorless | solubility - | solubility water: soluble |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 300 |
| form powder | form powder | form powder | form powder |
| storage temp. 2-8°C | storage temp. - | storage temp. - | storage temp. room temp |
| mp 91 - 93 °C ((196 - 199 °F )) | mp 172-175 °C (lit.) | mp 219 °C (dec.) | mp 160 °C (dec.) (lit.) |
Lagerklasse
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdfHelpful?
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Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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