M216

MDL 105,519

≥98% (HPLC), NMDA receptor antagonist, solid

• Synonym(e): (E)-4,6-Dichloro-3-(2-phenyl-2-carboxyethenyl)indole-2-carboxylic acid
• Empirische Formel (Hill-System): C₁₈H₁₁Cl₂NO₄
• CAS-Nummer: 161230-88-2
• Molekulargewicht: 376.19
• UNSPSC Code: 12352200
• PubChem Substance ID: 24277992
• NACRES: NA.32
• MDL number: MFCD00935267

Eigenschaften

• Produktname: MDL 105,519, ≥98% (HPLC), solid
• Quality Level: 100
• assay: ≥98% (HPLC)
• form: solid
• color: white to off-white
• solubility: DMSO: >20 mg/mL
• SMILES string: OC(=O)C(=C/c1c([nH]c2cc(Cl)cc(Cl)c12)C(O)=O)\c3ccccc3
• InChI: 1S/C18H11Cl2NO4/c19-10-6-13(20)15-12(16(18(24)25)21-14(15)7-10)8-11(17(22)23)9-4-2-1-3-5-9/h1-8,21H,(H,22,23)(H,24,25)/b11-8-
• InChI key: LPWVUDLZUVBQGP-FLIBITNWSA-N
• Gene Information: human ... GRIN1(2902) ; rat ... Grin1(24408)

Beschreibung

Biochem/physiol Actions

MDL 105,519 is a high affinity N-methyl-D-aspartate (NMDA) glutamate receptor antagonist at the glycine site. It inhibits NMDA-dependent responses.

Legal Information

Sold under exclusive license from Hoechst Marion Roussel, Inc.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)