L2506

β-Lactoglobulin aus Kuhmilch

≥85% (PAGE), lyophilized powder

• Synonym(e): β-LG, Bos d 5, beta-LG
• CAS-Nummer: 9045-23-2
• UNSPSC Code: 12352202
• EC Number: 232-928-9
• NACRES: NA.61
• MDL number: MFCD00130635
• Form: lyophilized powder
• Assay: ≥85% (PAGE)
• Biological source: bovine milk

Eigenschaften

• biological source: bovine milk
• Quality Segment: 200
• assay: ≥85% (PAGE)
• form: lyophilized powder
• technique(s): titration: suitable
• UniProt accession no.: P02754
• storage temp.: 2-8°C
• Gene Information: bovine ... LGB(280838)

Beschreibung

General description

β-Lactoglobulin plays a key role in immune response and modulates IgM levels and cell proliferation. β-Lactoglobulin from bovine is a model system for protein folding studies and denaturation kinetics. Polymorphisms in the β-lactoglobulin modulates bovine milk production and composition.

A member of the lipocalin family, βLg is a small protein of 162 amino acids with a molecular mass of ∼18,400 Da,. It has an eight-stranded β-barrel (strands A-H) succeeded by a three-turn a-helix and a final β-strand (strand I) that forms part of the dimerization interface.[1]

Milk from dairy cows contains the protein β-lactoglobulin (BLG). It naturally occurs in a number of genetic variants, and the most prevalent bovine variants are BLG A and BLG B.[2]

Application

β-Lactoglobulin from bovine milk has been used:

• for the generation of calibration curve for protein solubility index
• in acid-base titration
• as a standard for surface hydrophobicity analysis

β-Lactoglobulin was used in a cytologic assay for diagnosis of food hypersensitivity in patients with irritable bowel syndrome.[3]

Analysis Note

Contains β-lactoglobulins A and B which can be isolated chromatographically.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)