G4923

(E)-Guggulsteron

≥95% (HPLC), powder

• Synonym(e): (17E)-Pregna-4,17(20)-dien-3,16-dion
• Empirische Formel (Hill-System): C₂₁H₂₈O₂
• CAS-Nummer: 39025-24-6
• Molekulargewicht: 312.45
• NACRES: NA.77
• PubChem Substance ID: 329799934
• UNSPSC Code: 12352205
• MDL number: MFCD01310758

Eigenschaften

• Quality Level: 100
• assay: ≥95% (HPLC)
• form: powder
• color: white to off-white
• solubility: DMSO: soluble 5 mg/mL
• functional group: ketone
• shipped in: ambient
• storage temp.: 2-8°C
• SMILES string: C\C=C1\C(=O)C[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C
• InChI: 1S/C21H28O2/c1-4-16-19(23)12-18-15-6-5-13-11-14(22)7-9-20(13,2)17(15)8-10-21(16,18)3/h4,11,15,17-18H,5-10,12H2,1-3H3/b16-4-/t15-,17+,18+,20+,21-/m1/s1
• InChI key: WDXRGPWQVHZTQJ-AUKWTSKRSA-N

Beschreibung

Biochem/physiol Actions

Naturally occuring bioactive plant sterol isolated from the gum resin of guggul (Commiphora wightii). Antihyperlipidemic. Induces the expression of human CYP3A.

Naturally occuring bioactive plant sterol isolated from the gum resin of guggul (Commiphora wightii). Antihyperlipidemic. Induces the expression of human CYP3A.. Guggulsterone potently reverses multi-drug resistance in a number of human cancer cell lines, extending the efficacy of chemotherapy.

Sicherheitshinweise

• pictograms: GHS07
• signalword: Warning
• hcodes: H335,H412
• pcodes: P261 - P271 - P273 - P304 + P340 + P312 - P403 + P233 - P405
• Hazard Classifications: Aquatic Chronic 3 - STOT SE 3
• target_organs: Respiratory system
• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable