This product is native fetuin isolated from fetal bovine serum and should contain both Fetuin A and B. The percentage of each is not determined. It is prepared by ammonium sulfate fractionation of fetal bovine serum by the method of Pederson, K.O., J. Phys. and Colloid Chem., 51, 164 (1947). The article indicates that the preparation was carried out to obtain both alpha and beta forms of Fetuin. For more information, see https://pubmed.ncbi.nlm.nih.gov/20286396/
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F3004
Fetuin from fetal bovine serum
lyophilized powder
Synonym(e):
Fetuin aus Kälberserum fötal
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| Packungsgröße | SKU | Verfügbarkeit | Preis |
|---|---|---|---|
| 25 mg | Warenkorb auf Verfügbarkeit prüfen | € 71,30 | |
| 100 mg | Warenkorb auf Verfügbarkeit prüfen | € 203,00 | |
| 250 mg | Warenkorb auf Verfügbarkeit prüfen | € 334,00 | |
| 1 g | Warenkorb auf Verfügbarkeit prüfen | € 1.070,00 |
Über diesen Artikel
Form:
lyophilized powder
Biological source:
bovine serum (fetal)
Technischer Dienst
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Unterstützung erhaltenbiological source
bovine serum (fetal)
Quality Segment
form
lyophilized powder
technique(s)
HPLC: suitable, MALDI-MS: suitable
impurities
~0.2% free N-acetylneuraminic acid
UniProt accession no.
storage temp.
2-8°C
Gene Information
bovine ... FETUB(504615)
General description
Fetuin is an abundant glycosylated protein from fetal bovine serum and functions as a transport and storage protein. It is also called the α2-Heremans-Schmid glycoprotein (AHSG) and corresponds to a molecular weight of 64 kDa. It belongs to the statin family and is synthesized principally in the liver and partially in the kidneys, placenta and the tongue.
Application
Fetuin from fetal bovine serum has been used:
- as a standard glycoprotein in matrix-assisted laser desorption/ionization-mass spectrometry (MALDI-MS) and high-performance liquid chromatography-fluorescence detection analysis (HPLC-FLD)
- as a ligand in carbohydrate binding assay of pertussis toxin vaccine
- in the synthesis of fetuin-A conjugated gold nanoparticles (F-GNPs) for drug carrier studies[1]
Biochem/physiol Actions
In humans, polymorphism in the fetuin gene is implicated in type 2 diabetes mellitus and modulates adipocyte functionality. Elevated level of fetuin is observed in obesity and nonalcoholic fatty liver diseases (NAFLD). Fetuin is a potential marker in clinical diagnosis of metabolic disorders.
Preparation Note
Further processing of F2379 by gel filtration.
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Dieser Artikel | |||
|---|---|---|---|
| biological source bovine serum (fetal) | biological source - | biological source bovine serum (fetal) | biological source bovine serum |
| technique(s) HPLC: suitable, MALDI-MS: suitable | technique(s) cell culture | mammalian: suitable | technique(s) cell culture | mammalian: suitable | technique(s) cell culture | mammalian: suitable |
| form lyophilized powder | form lyophilized powder | form lyophilized powder | form lyophilized solid |
| impurities ~0.2% free N-acetylneuraminic acid | impurities ≤0.3% free N-acetylneuraminic acid | impurities ≤0.3% free N-acetylneuraminic acid | impurities - |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. −20°C |
| Gene Information bovine ... FETUB(504615) | Gene Information - | Gene Information bovine ... FETUA(504615) | Gene Information bovine ... AHSG(280988), FETUB(504615) |
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Lagerklasse
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Verwandter Inhalt
Product Information Sheet
Global Trade Item Number
| SKU | GTIN |
|---|---|
| F3004-100MG | 04061833613443 |
| F3004-1G | 04061826667064 |
| F3004-25MG | 04061833270967 |
| F3004-250MG | 04061833613450 |
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製品にFetuin-Aが含まれることはありますでしょうか？
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