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E0251

Estrone 3-sulfate sodium salt

Name: Estrone 3-sulfate sodium salt
Brand: SIGMA
Price: 381 EUR

synthetic (organic), ≥98% (TLC), Inactive estrogen, powder

Synonym(e):

1,3,5(10)-Estratrien-17-one 3-sulfate

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Packungsgröße	SKU	Verfügbarkeit	Preis
100 mg		Warenkorb auf Verfügbarkeit prüfen	€ 381,00
1 g		Warenkorb auf Verfügbarkeit prüfen	€ 1.010,00

Über diesen Artikel

Lineare Formel:

C₁₈H₂₁O₅SNa

CAS-Nummer:

438-67-5

Molekulargewicht:

372.41

UNSPSC Code:

12352202

PubChem Substance ID:

24894364

NACRES:

NA.77

MDL number:

MFCD00070035

Assay:

≥98% (TLC)

Form:

powder

Quality level:

200

€ 381,00

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Unterstützung erhalten

Produktname

Estrone 3-sulfate sodium salt, contains ~35% Tris as stabilizer

biological source

synthetic (organic)

Quality Level

200

sterility

non-sterile

assay

≥98% (TLC)

form

powder

contains

~35% Tris as stabilizer

technique(s)

inhibition assay: suitable

solubility

methanol: 19.60-20.40 mg/mL, clear, colorless to faintly yellow

shipped in

ambient

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Dieser Artikel	E1752	E9505	E6375
Sigma-Aldrich E0251 Estrone 3-sulfate sodium salt	Sigma-Aldrich E1752 Estrone 3-(β-D-glucuronide) sodium salt	Sigma-Aldrich E9505 β-Estradiol 3-sulfate sodium salt	Sigma-Aldrich E6375 Estriol 3-sulfate sodium salt
form powder	form powder	form powder	form powder
technique(s) inhibition assay: suitable	technique(s) ELISA: suitable	technique(s) -	technique(s) -
assay ≥98% (TLC)	assay ≥99% (HPLC)	assay ≥93%	assay ≥98% (TLC)
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level 200
solubility methanol: 19.60-20.40 mg/mL, clear, colorless to faintly yellow	solubility water: 20 mg/mL, clear, colorless	solubility methanol: 9.80-10.20 mg/mL, clear, colorless to faintly yellow	solubility methanol: 19.60-20.40 mg/mL, clear, colorless to faintly yellow
storage temp. −20°C	storage temp. −20°C	storage temp. room temp	storage temp. room temp

Features and Benefits

This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Packaging

Package size based on steroid content

pictograms

GHS08

signalword

Danger

hcodes

H351,H360,H362

pcodes

P202 - P260 - P263 - P264 - P270 - P308 + P313

Hazard Classifications

Carc. 2 - Lact. - Repr. 1A

Lagerklasse

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number

0000508192

0000519056

0000481181

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Comparison of different regimens of estradiol benzoate treatments followed by long-acting progesterone to prepare noncycling mares as embryo recipients.

E S M Silva et al.

Theriogenology, 86(7), 1749-1756 (2016-08-09)

The present study evaluated the influence of different regimens of estradiol benzoate (EB) treatments followed by a single dose of long-acting progesterone (LA P4) on plasma estrogen and P4 concentrations in noncyclic mares prepared as embryo recipients. Twenty-one anestrous mares

Estrogen and androgen receptor expression in relation to steroid concentrations in the adult boar epididymis.

Christopher A Pearl et al.

Domestic animal endocrinology, 33(4), 451-459 (2006-10-13)

The steroid hormone regulation of the epididymis in a high estrogen producing animal like the boar is not currently understood. To test the hypothesis that the boar epididymis is an estrogen and androgen responsive tissue, the presence of estrogen and

Suppression of cell proliferation by inhibition of estrone-3-sulfate transporter in estrogen-dependent breast cancer cells.

Takashi Nozawa et al.

Pharmaceutical research, 22(10), 1634-1641 (2005-09-24)

The aim of the study is to suppress the progress of estrogen-dependent breast cancer by inhibiting the membrane transporter, which mediates the internalization of estrone-3-sulfate as estrogen precursor in the cancer cells. The uptake of estrone-3-sulfate by estrogen-dependent breast cancer

Estrone-3-Sulfate Stimulates the Proliferation of T47D Breast Cancer Cells Stably Transfected With the Sodium-Dependent Organic Anion Transporter SOAT (SLC10A6).

Emre Karakus et al.

Frontiers in pharmacology, 9, 941-941 (2018-09-07)

Estrogens play a pivotal role in the development and proliferation of hormone-dependent breast cancer. Apart from free estrogens, which can directly activate the estrogen receptor (ER) of tumor cells, sulfo-conjugated steroids, which maintain high plasma concentrations even after menopause, first

Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.

Maria Karlgren et al.

Journal of medicinal chemistry, 55(10), 4740-4763 (2012-05-01)

The hepatic organic anion transporting polypeptides (OATPs) influence the pharmacokinetics of several drug classes and are involved in many clinical drug-drug interactions. Predicting potential interactions with OATPs is, therefore, of value. Here, we developed in vitro and in silico models

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Global Trade Item Number

SKU	GTIN
E0251-100MG	04061833600986
E0251-1G	04061826236451

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