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Merck

D9190

DCEBIO

≥98% (HPLC), solid

Synonym(e):

5,6-Dichloro-1-ethyl-1,3-dihydro-2H-benzimidazole-2-one

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Über diesen Artikel

Empirische Formel (Hill-System):
C9H8N2OCl2
CAS-Nummer:
Molekulargewicht:
231.08
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
solid
Quality level:

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Quality Level

assay

≥98% (HPLC)

form

solid

color

white to off-white

solubility

DMSO: >10 mg/mL

SMILES string

CCN1C(=O)Nc2cc(Cl)c(Cl)cc12

InChI

1S/C9H8Cl2N2O/c1-2-13-8-4-6(11)5(10)3-7(8)12-9(13)14/h3-4H,2H2,1H3,(H,12,14)

InChI key

LKHRMULASXZCLG-UHFFFAOYSA-N

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Dieser Artikel
C125E1279C5366
assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

-

assay

≥98% (HPLC)

form

solid

form

solid

form

solid

form

solid

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

-

solubility

DMSO: >10 mg/mL

solubility

DMSO: >10 mg/mL

solubility

DMSO: soluble 28 mg/mL

solubility

H2O: ≥2 mg/mL, DMSO: >20 mg/mL

color

white to off-white

color

white

color

light yellow

color

white

Gene Information

human ... HTR1A(3350), HTR1B(3351), HTR1D(3352), HTR1E(3354), HTR1F(3355), HTR2A(3356), HTR2B(3357), HTR2C(3358), HTR3A(3359), HTR3B(9177), HTR3C(170572), HTR3D(200909), HTR3E(285242), HTR4(3360), HTR5A(3361), HTR5B(645694), HTR6(3362), HTR7(3363)

Gene Information

human ... ADRB1(153), ADRB2(154), ADRB3(155)

Gene Information

human ... PDE3A(5139), PDE3B(5140)

Gene Information

-

Biochem/physiol Actions

DCEBIO facilitates Cl secretion in the epithelia by activating K+ and Cl currents.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Lagerklasse

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 48(6), 2374-2388 (2018-08-17)
Intermediate-conductance Ca2+-activated K+ (IKCa; KCa3.1 or KCNN4) channels affect the behaviors of central neurons including motor neurons. The mechanism through which neuronal differentiation is related to the activity of these channels remains largely unclear. By using various molecular biology tools

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