D5564

7,8-Dihydroxycumarin

≥97%, powder

• Synonym(e): Daphnetin, Daphnetol, Ruixiangsu
• Empirische Formel (Hill-System): C₉H₆O₄
• CAS-Nummer: 486-35-1
• Molekulargewicht: 178.14
• NACRES: NA.77
• PubChem Substance ID: 24278375
• UNSPSC Code: 12352200
• EC Number: 207-632-8
• MDL number: MFCD00016977
• Assay: ≥97%
• Form: powder
• Quality level: 200

Eigenschaften

• InChI key: ATEFPOUAMCWAQS-UHFFFAOYSA-N
• InChI: 1S/C9H6O4/c10-6-3-1-5-2-4-7(11)13-9(5)8(6)12/h1-4,10,12H
• SMILES string: Oc1ccc2C=CC(=O)Oc2c1O
• biological source: synthetic (organic)
• assay: ≥97%
• form: powder
• solubility: ethanol: 5 mg/mL
• storage temp.: room temp
• Quality Level: 200

Beschreibung

Biochem/physiol Actions

7,8-Dihydroxycoumarinan is an inhibitor of protein kinases. It is an active lactone present in plants such as Daphne Korean Nakai,[1] and Thymelaeaceae Daphne.[2] It serves as as analgesic, antiviral and antibacterial agent. 7,8-Dihydroxycoumarinan is found to induce tumor apoptosis via a number of signalling pathways. Thus, it is believed to exhibit antitumor effects. 7,8-Dihydroxycoumarinan might also be useful in treating lung carcinoma.[1] It is also known to be used in treating coagulation disorders and rheumatoid arthritis. 7,8-Dihydroxycoumarinan is known to induce neurite growth and lengthen neuronal survival.[3] It helps in clearing substances inducing necrosis, maintains water-electrolytes balance and energy metabolism. 7,8-Dihydroxycoumarinan is involved in the generation of neurotrophic factor and helps in restoring neuron function.[2]

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)