D3689

(S)-3,5-Dihydroxyphenylglycine hydrate

≥98% (HPLC), group I metabotropic glutamate receptor agonist, powder

• Synonym(e): S-DHPG
• Empirische Formel (Hill-System): C₈H₉NO₄ · xH₂O
• CAS-Nummer: 162870-29-3
• Molekulargewicht: 183.16 (anhydrous basis)
• UNSPSC Code: 12352209
• PubChem Substance ID: 24278366
• NACRES: NA.77
• MDL number: MFCD11044457
• Assay: ≥98% (HPLC)
• Form: powder
• Storage condition: desiccated, protect from light

Eigenschaften

• Produktname: (S)-3,5-Dihydroxyphenylglycine hydrate, ≥98% (HPLC), powder
• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated, protect from light
• color: white
• storage temp.: −20°C
• SMILES string: O.N[C@H](C(O)=O)c1cc(O)cc(O)c1
• InChI: 1S/C8H9NO4.H2O/c9-7(8(12)13)4-1-5(10)3-6(11)2-4;/h1-3,7,10-11H,9H2,(H,12,13);1H2/t7-;/m0./s1
• InChI key: QZEFIWWBQUKNFA-FJXQXJEOSA-N
• Gene Information: human ... GRM1(2911)

Beschreibung

Application

(S)-3,5-Dihydroxyphenylglycine hydrate has been used:

• as mGluR1/5 agonist for metabotropic glutamate receptor 1 (mGluR1/5) activation in synaptoneurosomal preparations
• in ACSF for DHPG stimulation
• to inject into basolateral amygdala to study its effect on memory expression

Biochem/physiol Actions

(S)-3,5-Dihydroxyphenylglycine hydrate is a group I metabotropic glutamate receptor agonist.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Disclaimer

air sensitive

Sicherheitshinweise

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves