D3630

Diphenhydramin -hydrochlorid

≥98% (HPLC)

• Synonym(e): 2-Diphenylmethoxy-N,N-dimethylethylamin -hydrochlorid, N-(2-Diphenylmethoxyethyl)-N,N-dimethylamin -hydrochlorid
• Empirische Formel (Hill-System): C₁₇H₂₁NO · HCl
• CAS-Nummer: 147-24-0
• Molekulargewicht: 291.82
• EG-Nummer: 205-687-2
• MDL-Nummer: MFCD00012479
• UNSPSC-Code: 12352116
• PubChem Substanz-ID: 24277771
• NACRES: NA.77

Eigenschaften

• Assay: ≥98% (HPLC)
• Form: powder
• Ersteller: Johnson & Johnson
• SMILES String: Cl[H].CN(C)CCOC(c1ccccc1)c2ccccc2
• InChI: 1S/C17H21NO.ClH/c1-18(2)13-14-19-17(15-9-5-3-6-10-15)16-11-7-4-8-12-16;/h3-12,17H,13-14H2,1-2H3;1H
• InChIKey: PCHPORCSPXIHLZ-UHFFFAOYSA-N
• Angaben zum Gen: human ... HRH1(3269)

Beschreibung

Anwendung

Diphenhydramine hydrochloride has been used:
as a reference compound to study the long duration of action of antihistamine bilastine in vivo
to detect its embryotoxicity by embryonic stem cell test (EST) using cardiomyocyte differentiation and osteoblasts differentiation
as an antihistamine in experimental studies

Biochem./physiol. Wirkung

H1 histamine receptor antagonist
Diphenhydramine hydrochloride (DPH) is an antihistaminic agent that relieves symptoms of hypersensitive reactions. It exhibits antimuscarinic and marked sedative effects. DPH is also used to prevent nausea, vomiting and vertigo of various causes. In addition, it acts as a potential therapeutic for insomnia.

Leistungsmerkmale und Vorteile

This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302
• P-Sätze: P264 - P270 - P301 + P312 - P501
• Gefahreneinstufungen: Acute Tox. 4 Oral
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Faceshields, Gloves