C5865

CD437

≥98% (HPLC), retinoic acid receptor (RAR)γ-selective agonist, solid

• Synonym(e): 6-[3-(1-Adamantyl)-4-hydroxyphenyl]-2-naphthalene carboxylic acid, AHPN
• Empirische Formel (Hill-System): C₂₇H₂₆O₃
• CAS-Nummer: 125316-60-1
• Molekulargewicht: 398.49
• UNSPSC Code: 12352200
• PubChem Substance ID: 24724445
• NACRES: NA.77
• MDL number: MFCD03106506
• Assay: ≥98% (HPLC)
• Form: solid
• Quality level: 100

Eigenschaften

• Produktname: CD437, ≥98% (HPLC), solid
• Quality Level: 100
• assay: ≥98% (HPLC)
• form: solid
• impurities: ~0.5 mol/mol water
• color: yellow
• mp: 271.6-276 °C
• solubility: DMSO: >10 mg/mL, H₂O: insoluble
• storage temp.: −20°C
• SMILES string: OC(=O)c1ccc2cc(ccc2c1)-c3ccc(O)c(c3)C45CC6CC(CC(C6)C4)C5
• InChI: 1S/C27H26O3/c28-25-6-5-22(20-1-2-21-11-23(26(29)30)4-3-19(21)10-20)12-24(25)27-13-16-7-17(14-27)9-18(8-16)15-27/h1-6,10-12,16-18,28H,7-9,13-15H2,(H,29,30)
• InChI key: LDGIHZJOIQSHPB-UHFFFAOYSA-N
• Gene Information: human ... RARA(5914), RARB(5915), RARG(5916)

Beschreibung

Biochem/physiol Actions

CD437 is a retinoic acid receptor (RAR)γ-selective agonist, γ-selective retinoid; potent inducer of apoptosis.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)