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C2196

Sigma-Aldrich

L-Cystein-S-Sulfat

≥98% (TLC), suitable for ligand binding assays

Synonym(e):

S-Sulfo-L-cystein

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About This Item

Empirische Formel (Hill-System):
C3H7NO5S2
CAS-Nummer:
1637-71-4
Molekulargewicht:
201.22
Beilstein:
1726832
MDL-Nummer:
MFCD00133440
UNSPSC-Code:
12352209
PubChem Substanz-ID:
24892471
NACRES:
NA.26

product name

L-Cystein-S-Sulfat, ≥98% (TLC)

Qualitätsniveau

200

Assay

≥98% (TLC)

Form

powder

Methode(n)

ligand binding assay: suitable

Farbe

white

Lagertemp.

−20°C

SMILES String

N[C@@H](CSS(O)(=O)=O)C(O)=O

InChI

1S/C3H7NO5S2/c4-2(3(5)6)1-10-11(7,8)9/h2H,1,4H2,(H,5,6)(H,7,8,9)/t2-/m0/s1

InChIKey

NOKPBJYHPHHWAN-REOHCLBHSA-N

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Verwandte Kategorien

Biochem./physiol. Wirkung

L-Cysteine S-sulfate (LCSS) is used as an NMDA glutamatergic receptor agonist. It serves as a substrate for cystine lyase(s).
Cysteine is one of the functional amino acids that are associated with growth, reproduction, maintenance and immunity. Cysteine is a source of disulfide linkage in protein and is associated with sulfur transport. At physiological pH, cysteine undergoes rapid oxidation to form cystine. Reduced availability of cysteine or cystine, influences leukocyte metabolism. L-Cysteine serves as a precursor for the rate limiting step in glutathione synthesis that occurs in neurons. It donates inorganic sulfate for detoxification reactions. Therefore, L-cysteine might be associated with neuroprotection. It is found to obstruct the entry of heavy metal ions across the blood-brain barrier into the brain. Increased levels of L-cysteine might lead to neurotoxicity.

Piktogramme

Exclamation mark
GHS07

Signalwort

Warning

Gefahreneinstufungen

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Zielorgane

Respiratory system

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Sigma-Aldrich

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Sigma-Aldrich

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Emma E Hobson et al.
European journal of pediatrics, 164(11), 655-659 (2005-07-19)
Isolated sulphite oxidase deficiency (ISOD) is a rare autosomal recessive inborn error of metabolism, which may present at birth with intractable seizures (often of prenatal onset) and severe neurological abnormalities. In infants who survive, lens dislocation may occur from 8
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Molybdenum cofactor deficiency is a rare autosomal recessive disorder with devastating neurological manifestations, characterised by neonatal-onset encephalopathy mimicking hypoxic-ischaemic insult, intractable seizure, and feeding and respiratory difficulties. It is often fatal in the early life. We report an affected 8-year-old
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