C1159
L-Cycloserin
≥95% (TLC), ketosphinganine synthetase inhibitor, powder
Synonym(e):
(S)-4-Amino-3-isoxazolidon
Anmelden zur Ansicht der Organisations- und Vertragspreise.
Größe auswählen
10 MG
€ 52,00
25 MG
€ 66,90
100 MG
€ 169,00
250 MG
€ 355,00
Über diesen Artikel
Empirische Formel (Hill-System):
C3H6N2O2
CAS-Nummer:
Molekulargewicht:
102.09
NACRES:
NA.77
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352202
EC Number:
206-427-0
MDL number:
Beilstein/REAXYS Number:
80799
Fortfahren mit
Technischer Dienst
Benötigen Sie Hilfe? Unser Team von erfahrenen Wissenschaftlern ist für Sie da.
Unterstützung erhaltenProduktname
L-Cycloserin,
InChI key
DYDCUQKUCUHJBH-REOHCLBHSA-N
InChI
1S/C3H6N2O2/c4-2-1-7-5-3(2)6/h2H,1,4H2,(H,5,6)/t2-/m0/s1
SMILES string
N[C@H]1CONC1=O
assay
≥95% (TLC)
form
powder
mp
146 °C
solubility
H2O: 50 mg/mg protein
storage temp.
−20°C
Quality Level
Verwandte Kategorien
1 of 4
Dieser Artikel | |||
|---|---|---|---|
| assay ≥95% (TLC) | assay ≥98.0% (TLC) | assay ≥99.0% (TLC) | assay ≥96% (TLC) |
| Quality Level 200 | Quality Level 200 | Quality Level 100 | Quality Level 100 |
| form powder | form powder | form powder | form powder |
| storage temp. −20°C | storage temp. −20°C | storage temp. 2-8°C | storage temp. 2-8°C |
| solubility H2O: 50 mg/mg protein | solubility - | solubility - | solubility - |
| mp 146 °C | mp - | mp 235-239 °C | mp - |
Biochem/physiol Actions
Blocks sphingosine biosynthesis by inhibition of ketosphinganine synthetase. Cytotoxicity toward neuroblastoma and medulloblastoma cells mediated by suppression of ganglioside synthesis.[1]
L-cycloserine is a potent inhibitor of serine palmitoyltransferase, the first step of sphingolipid synthesis.
Blocks sphingosine biosynthesis by inhibition of ketosphinganine synthetase. Cytotoxicity toward neuroblastoma and medulloblastoma cells mediated by suppression of ganglioside synthesis.[1]
Lagerklasse
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Hier finden Sie alle aktuellen Versionen:
Besitzen Sie dieses Produkt bereits?
In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.
Elisa Caiola et al.
Cells, 9(8) (2020-07-29)
Non-small-cell lung cancer (NSCLC) cell lines vary in their sensitivity to glutaminase inhibitors, so it is important to identify the metabolic assets underling their efficacy in cancer cells. Even though specific genetic lesions such as in KRAS and LKB1 have
Kerrie Davies et al.
Open forum infectious diseases, 7(11), ofaa362-ofaa362 (2020-11-19)
Lower Clostridium difficile spore counts in feces from C difficile infection (CDI) patients treated with fidaxomicin versus vancomycin have been observed. We aimed to determine whether environmental contamination is lower in patients treated with fidaxomicin compared with those treated with
Geraldine Rath et al.
The international journal of biochemistry & cell biology, 41(5), 1165-1172 (2008-11-26)
Doxorubicin and camptothecin are two cytotoxic chemotherapeutic agents triggering apoptosis in various cancer cells, including thyroid carcinoma cells. Recent studies revealed a critical role of ceramide in chemotherapy and suggested that anti-cancer drugs may kill tumor cells through sphingomyelinase activation.
Domenico Sergi et al.
Nutritional neuroscience, 23(4), 321-334 (2018-07-24)
A high-fat diet induces hypothalamic inflammation in rodents which, in turn, contributes to the development of obesity by eliciting both insulin and leptin resistance. However, the mechanism by which long-chain saturated fatty acids trigger inflammation is still contentious. To elucidate
Sara Ghezzal et al.
Biochimica et biophysica acta. Molecular and cell biology of lipids, 1865(2), 158530-158530 (2019-10-28)
The mechanisms leading to the low-grade inflammation observed during obesity are not fully understood. Seeking the initiating events, we tested the hypothesis that the intestine could be damaged by repeated lipid supply and therefore participate in inflammation. In mice, 1-5
Active Filters
Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..
Setzen Sie sich mit dem technischen Dienst in Verbindung