C0256

Cytidin 5′-Diphosphocholin Natriumsalz Dihydrat

~98%, from yeast, solid

• Synonym(e): CDP-Colin, CDP-cholin-Na, Citicolin Natrium, P′-[2-(Trimethylammonium)-­ethyl]-­ester-cytidin-5′-(tri­hydro­gendi­phos­phat) inneres Mononatriumsalz
• Empirische Formel (Hill-System): C₁₄H₂₅N₄NaO₁₁P₂ · 2H₂O
• CAS-Nummer: 33818-15-4
• Molekulargewicht: 546.34
• UNSPSC Code: 41106300
• NACRES: NA.77
• PubChem Substance ID: 24278064
• MDL number: MFCD00150508
• Beilstein/REAXYS Number: 4110040
• Assay: ~98%
• Form: solid

Eigenschaften

• biological source: yeast
• Quality Segment: 200
• assay: ~98%
• form: solid
• color: white
• solubility: H₂O: 100 mg/mL
• storage temp.: −20°C
• SMILES string: [Na+].C[N+](C)(C)CCOP([O-])(=O)OP([O-])(=O)OCC1OC([C@H](O)[C@@H]1O)N2C=CC(N)=NC2=O
• InChI: 1S/C14H26N4O11P2.Na/c1-18(2,3)6-7-26-30(22,23)29-31(24,25)27-8-9-11(19)12(20)13(28-9)17-5-4-10(15)16-14(17)21;/h4-5,9,11-13,19-20H,6-8H2,1-3H3,(H3-,15,16,21,22,23,24,25);/q;+1/p-1/t9?,11-,12-,13?;/m1./s1
• InChI key: YWAFNFGRBBBSPD-MBWJOHGMSA-M

Beschreibung

General description

Cytidine 5′-diphosphocholine (CDP-choline) contains cytidine and choline linked via a diphosphate bridge.

Application

Cytidine 5′-diphosphocholine sodium salt dihydrate has been used as a physiological metabolite for the identification of gemcitabine diphosphate choline (GdPC) by liquid chromatography-mass spectrometry (LC-MS/MS) method in the Kennedy pathway [1].

Biochem/physiol Actions

Cytidine 5′-diphosphocholine (CDP-choline) plays an important role in the synthesis of phosphatidylcholine. It is also involved in the biosynthesis of acetylcholine, a neurotransmitter. CDP-choline has therapeutic effects against hypoxia, cerebral ischemia and traumatic brain injury. It also exhibits therapeutic effects against learning and memory disorders, drug addiction and Alzheimer′s and Parkinson′s diseases.

Disclaimer

Hygroscopic

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)