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A0384

Arcaine sulfate salt

Synonym(e):

1,4-Diguanidinobutane sulfate salt

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PackungsgrößeSKUVerfügbarkeitPreis
50 mg
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€ 108,00

Über diesen Artikel

Empirische Formel (Hill-System):
C6H16N6 · H2O4S
CAS-Nummer:
14923-17-2
Molekulargewicht:
270.31
NACRES:
NA.77
PubChem Substance ID:
24277954
UNSPSC Code:
12352200
MDL number:
MFCD00050545
Assay:
≥98% (TLC)
Form:
powder
Quality level:
200

€ 108,00

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Unterstützung erhalten

biological source

synthetic (organic)

Quality Level

200

assay

≥98% (TLC)

form

powder

mp

>280 °C

solubility

1 M NaOH: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow

SMILES string

OS(O)(=O)=O.NC(=N)NCCCCNC(N)=N

InChI

1S/C6H16N6.H2O4S/c7-5(8)11-3-1-2-4-12-6(9)10;1-5(2,3)4/h1-4H2,(H4,7,8,11)(H4,9,10,12);(H2,1,2,3,4)

InChI key

RWTGFMPOODRXIM-UHFFFAOYSA-N

Gene Information

human ... GRIN1(2902), GRIN2A(2903), GRIN2B(2904), GRIN2C(2905), GRIN2D(2906), GRINA(2907)

Application

Arcaine sulfate salt has been used as an N-methyl-d-aspartate (NMDA) receptor effector/antagonist:
  • to evaluate its effects on the acquisition of electrical kindling of the amygdala[1]
  • to compare its effects with agmatine and MK801 on NMDA- or glutamate-induced neuronal damage[2]
  • to study its effects on cell-free translation of synthetic polynucleotide[3]

Biochem/physiol Actions

Arcaine sulfate salt (1,4-diguanidinobutane), a polyamine,[3] is an antagonist of the polyamine binding site of the N-methyl-d-aspartate (NMDA) receptor.[4] Arcaine, an agmatine analog,[2] along with ifenprodil, might have a possibility for therapeutic management in epileptic disorders.[1]

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Dieser Artikel
M7033A7127H7278
Arcaine sulfate salt

Sigma-Aldrich

A0384

Arcaine sulfate salt

NG-Methyl-L-arginine acetate salt ≥98% (TLC)

Sigma-Aldrich

M7033

NG-Methyl-L-arginine acetate salt

Agmatine sulfate salt ≥97%, powder

Sigma-Aldrich

A7127

Agmatine sulfate salt

NG-Hydroxy-L-arginine acetate salt

Sigma-Aldrich

H7278

NG-Hydroxy-L-arginine acetate salt

assay

≥98% (TLC)

assay

≥98% (TLC)

assay

≥97%

assay

≥98% (TLC)

form

powder

form

powder

form

powder

form

powder

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

200

solubility

1 M NaOH: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow

solubility

water: 49.00-51.00 mg/mL, clear to very slightly hazy, colorless to faintly yellow

solubility

H2O: 50 mg/mL, ethanol: insoluble

solubility

acetic acid: 10 mg/mL, clear, colorless to faintly yellow

Gene Information

human ... GRIN1(2902), GRIN2A(2903), GRIN2B(2904), GRIN2C(2905), GRIN2D(2906), GRINA(2907)

Gene Information

human ... NOS1(4842), NOS2(4843), NOS3(4846)
mouse ... Nos2(18126)
rat ... Nos1(24598), Nos2(24599)

Gene Information

human ... ADRA2A(150), ADRA2B(151), ADRA2C(152), GRIN1(2902), GRIN2A(2903), GRIN2B(2904), GRIN2C(2905), GRIN2D(2906), GRINA(2907)

Gene Information

-

biological source

synthetic (organic)

biological source

-

biological source

-

biological source

-

Lagerklasse

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number
SLCL4063
SLCF8524
SLBT4233
SLBR2066V
SLBJ9045V

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Min-Ching Kuo et al.
The European journal of neuroscience, 27(7), 1731-1738 (2008-03-29)
Recent evidence indicates that the mature central visual system retains a higher degree of plasticity than traditionally assumed. However, little is known regarding the neuromodulatory factors that influence plasticity in the adult primary visual cortex (V1). We investigated the role
Nandkishor Ramdas Kotagale et al.
Behavioural brain research, 213(2), 161-174 (2010-05-11)
Agmatine [2-(4-aminobutyl)guanidine] is an endogenous amine proposed as a neurotransmitter/neuromodulator that binds to multiple target receptors in brain. Besides, many central and peripheral functions, agmatine have been implicated in the process of drug addiction. The purpose of the present study
Keli Camera et al.
Psychopharmacology, 192(4), 457-464 (2007-02-24)
The polyamines putrescine, spermine, and spermidine are a group of aliphatic amines that physiologically modulate the N-methyl-D-aspartate (NMDA) receptor, a glutamate receptor implicated in memory formation. Given the potential application of these drugs in the treatment of memory disorders, we
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Global Trade Item Number

SKUGTIN
A0384-50MG04061832088501

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