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89126
Cetirizin -dihydrochlorid
≥98.0% (HPLC)
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Über diesen Artikel
Empirische Formel (Hill-System):
C21H25ClN2O3 · 2HCl
CAS-Nummer:
Molekulargewicht:
461.81
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
Preise und Verfügbarkeit sind derzeit nicht verfügbar.
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Unterstützung erhaltenQuality Level
assay
≥98.0% (HPLC)
form
powder
SMILES string
Cl[H].Cl[H].OC(=O)COCCN1CCN(CC1)C(c2ccccc2)c3ccc(Cl)cc3
InChI
1S/C21H25ClN2O3.2ClH/c22-19-8-6-18(7-9-19)21(17-4-2-1-3-5-17)24-12-10-23(11-13-24)14-15-27-16-20(25)26;;/h1-9,21H,10-16H2,(H,25,26);2*1H
InChI key
PGLIUCLTXOYQMV-UHFFFAOYSA-N
Gene Information
human ... HRH1(3269)
Application
Cetirizin (CTZ) may be used in studies on the treatment of cutaneous mastocytosis (urticaria pigmentosa). Cetirizin, an antihistamine, may be useD in allergy research as an antagonist of the histamine 1 receptor (H1R).
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| assay ≥98.0% (HPLC) | assay ≥98% (HPLC) | assay - | assay - |
| form powder | form powder | form - | form - |
| Quality Level 100 | Quality Level 100 | Quality Level - | Quality Level - |
| Gene Information human ... HRH1(3269) | Gene Information human ... HRH1(3269) | Gene Information human ... HRH1(3269) | Gene Information human ... HRH1(3269) |
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M Gschwandtner et al.
Allergy, 68(1), 37-47 (2012-11-20)
Defects in keratinocyte differentiation and skin barrier are important features of inflammatory skin diseases like atopic dermatitis. Mast cells and their main mediator histamine are abundant in inflamed skin and thus may contribute to disease pathogenesis. Human primary keratinocytes were
K Rossbach et al.
Neuroscience, 190, 89-102 (2011-06-22)
Histamine has long been recognised as a classical inducer of pruritus. However, the specific mechanism of histamine-induced itch has still not been fully understood. The H1 and H4 receptor appear to be key components in the induction of itch. The
Ko-Haung Lue et al.
International journal of pediatric otorhinolaryngology, 76(7), 994-1001 (2012-04-20)
Supplementary consumption of probiotics may temporarily alter the intestinal microflora of infants and children, thereby preventing and treating allergic disorders. To compare the clinical efficacy of levocetirizine with that of levocetirizine plus Lactobacillus johnsonii EM1 (Lj EM1) for treating perennial
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 89126-1G-F | 04061826012376 |
| 89126-50MG-F | 04061832405407 |