69591

4-Methylumbelliferyl α-D-Glucopyranosid

≥98% (TLC)

• Synonym(e): 4-Methylumbelliferyl-α-D-glucosid
• Empirische Formel (Hill-System): C₁₆H₁₈O₈
• CAS-Nummer: 17833-43-1
• Molekulargewicht: 338.31
• UNSPSC Code: 12352204
• NACRES: NA.25
• PubChem Substance ID: 57652200
• EC Number: 241-794-0
• Beilstein/REAXYS Number: 1690776
• MDL number: MFCD00067661

Eigenschaften

• Quality Segment: 200
• description: α-glucosidase substrate
• assay: ≥98% (TLC)
• form: powder
• solubility: DMSO: 50 mg/mL, clear, colorless to faintly yellow
• fluorescence: λ_ex 316 nm; λ_em 375 nm (Reaction product), λ_ex 317 nm; λ_em 374 nm (pH9.0), λ_ex 360 nm; λ_em 449 nm, λ_ex 365 nm; λ_em 445 nm in 0.1 M Tris pH 8.0 (α-glucosidase)
• storage temp.: −20°C
• SMILES string: CC1=CC(=O)Oc2cc(O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)ccc12
• InChI: 1S/C16H18O8/c1-7-4-12(18)23-10-5-8(2-3-9(7)10)22-16-15(21)14(20)13(19)11(6-17)24-16/h2-5,11,13-17,19-21H,6H2,1H3/t11-,13-,14+,15-,16+/m1/s1
• InChI key: YUDPTGPSBJVHCN-JZYAIQKZSA-N

Beschreibung

General description

4-Methylumbelliferyl α-D-glucopyranoside is the fluorogenic substrate of alpha-glucosidase enzyme.[1] 4-Methylumbelliferyl α-D-glucopyranoside, also known as 4MU- α-glc, upon reaction leads to the product 4MU, which emits at the peak of 440nm in the fluorescence spectra.[2]

Application

4-Methylumbelliferyl α-D-glucopyranoside is used as a flurogenic substrate for the identification, characterization and kinetic analysis of α-D-glucosidase(s).4-Methylumbelliferyl α-D-glucopyranoside is used for high throughput screening experiments. It is suitable for the diagnosis of Pompe′s disease in kidney and leucocytes.[3]

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)