Fortfahren mit
53467
2,3-Dioleyloxy-1-(dimethylamino)-propan
≥98.0% (TLC)
Synonym(e):
1,2-Dioleyloxy-3-(dimethylamino)-propan, N,N-Dimethyl-2,3-bis-[(9Z)-9-octadecen-1-yloxy]-1-propanamin, DODMA
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| Packungsgröße | SKU | Verfügbarkeit | Preis |
|---|
Über diesen Artikel
Empirische Formel (Hill-System):
C41H81NO2
CAS-Nummer:
Molekulargewicht:
620.09
UNSPSC Code:
12352211
NACRES:
NA.85
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
10139013
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Technischer Dienst
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Unterstützung erhaltenbiological source
synthetic
Quality Level
assay
≥98.0% (TLC)
form
liquid
functional group
amine, ether
lipid type
cationic lipids
storage temp.
−20°C
SMILES string
CCCCCCCC\C=C/CCCCCCCCOCC(CN(C)C)OCCCCCCCC\C=C/CCCCCCCC
InChI
1S/C41H81NO2/c1-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-37-43-40-41(39-42(3)4)44-38-36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-2/h19-22,41H,5-18,23-40H2,1-4H3/b21-19-,22-20-
InChI key
GLGLUQVVDHRLQK-WRBBJXAJSA-N
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
1 of 1
Dieser Artikel | |||
|---|---|---|---|
| functional group amine, ether | functional group - | functional group amine | functional group amine |
| assay ≥98.0% (TLC) | assay 97% | assay 98% | assay ≥99% |
| biological source synthetic | biological source - | biological source - | biological source - |
| storage temp. −20°C | storage temp. - | storage temp. - | storage temp. - |
| form liquid | form liquid | form - | form - |
| Quality Level 100 | Quality Level 200 | Quality Level 200 | Quality Level 100 |
Lagerklasse
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Lloyd B Jeffs et al.
Pharmaceutical research, 22(3), 362-372 (2005-04-20)
A fully scalable and extrusion-free method was developed to prepare rapidly and reproducibly stabilized plasmid lipid particles (SPLP) for nonviral, systemic gene therapy. Liposomes encapsulating plasmid DNA were formed instantaneously by mixing lipids dissolved in ethanol with an aqueous solution
Cationic lipid saturation influences intracellular delivery of encapsulated nucleic acids.
Heyes, J., et al.
J. Controlled Release, 107, 276-287 (2005)
Adam Judge et al.
Molecular therapy : the journal of the American Society of Gene Therapy, 13(2), 328-337 (2005-11-09)
The systemic application of nucleic acid drugs requires delivery systems that overcome the poor pharmacokinetics, limited biodistribution, and inefficient uptake of nucleic acids. PEGylated liposomes show considerable promise because of their intrinsic ability to accumulate at disease sites and facilitate
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 53467-100MG | 04061833380840 |
| 53467-500MG | 04061833380857 |