H2O: 100 mg/mL, clear, colorless to faintly greenish-yellow
storage temp.
room temp
General description
Dextran is a polymer of anhydroglucose. It is composed of approximately 95% alpha-D-(166) linkages. The remaining (163) linkages account for the branching of dextran.
Application
Dextran sulfate is routinely used for the selective precipitation of lipoproteins, probe hybridization membrane-immobilized DNA, the release of DNA from DNA-histone complexes, and the inhibition of RNA binding to ribosomes.
Biochem/physiol Actions
Dextran sulfate inhibits the replication of the human immunodeficiency virus by preventing the adsorption of the virus into host cells. [1]
Other Notes
To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.
Proceedings of the National Academy of Sciences of the United States of America, 85(16), 6132-6136 (1988-08-01)
The sulfated polysaccharides dextran sulfate and heparin have proved to be potent and selective inhibitors of human immunodeficiency virus type 1 (HIV-1) in vitro. Dextran sulfate (Mr 5000) and heparin (Mr 15,000) completely protected MT-4 cells against HIV-1-induced cytopathogenicity at
