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44612

Durcupan ACM

single component B, hardener 964

Synonym(e):

ACM resins

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100 ML

€ 46,10

500 ML

€ 176,00

€ 46,10


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Über diesen Artikel

UNSPSC Code:
13111001
NACRES:
NA.25
MDL number:

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Dieser Artikel
L9774I475844611
Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

100

General description

A water-soluble embedding medium for EM based on an aliphatic polyepoxide.

Application

Durcupan ACM, single component B, hardener 964 has been used for:
  • Embedding material for electron microscopy.
  • A method to prepare large resin sections for counting myelinated axons in rodent CNS and PNS structures.: This study presents a technique using Durcupan ACM for preparing large resin sections, enhancing the analysis of myelinated axons in rodent central and peripheral nervous systems.
  • Three-dimensional immersive virtual reality for studying cellular compartments in 3D models from EM preparations of neural tissues.: This research utilizes Durcupan ACM in electron microscopy to create 3D models of neural tissues, facilitating studies via immersive virtual reality.
  • Long-term effect of prazosin and losartan administration on blood pressure, heart, carotid artery, and acetylcholine induced dilation of cardiovascular system of young Wistar rats and SHR.: Explores the cardiovascular effects in rats using Durcupan ACM embedded samples for detailed tissue analysis.

Features and Benefits

Mixtures of Durcupan ACM present an interesting alternative to methacrylates for embedding sections for electron microscopy. They present the advantage that they harden uniformly, practically without shrinkage. All fixing agents normally used for electron microscopic work are also suitable for the Durcupan ACM embedding process. This process consists of three phases: dehydration of the tissue with acetone or ethyl alcohol, infiltration with the embedding agent, followed by hardening.

Legal Information

Durcupan is a trademark of Sigma-Aldrich Chemie GmbH

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Hazard Classifications

Aquatic Chronic 4 - Eye Irrit. 2 - Skin Sens. 1

Lagerklasse

10 - Combustible liquids

flash_point_f

235.4 °F - closed cup

flash_point_c

113 °C - closed cup


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A method to prepare large resin sections for counting myelinated axons in rodent CNS and PNS structures
Dzurjaskova Z, et al.
Neuroscience Letters, 750, 135767-135767 (2021)
Long-term effect of prazosin and losartan administration on blood pressure, heart, carotid artery, and acetylcholine induced dilation of cardiovascular system of young Wistar rats and SHR
Kristek F, et al.
General Physiology and Biophysics, 32(2), 235?243-235?243 (2013)
Three-dimensional immersive virtual reality for studying cellular compartments in 3D models from EM preparations of neural tissues
Cali C, et al.
The Journal of Comparative Neurology, 524(1), 23-38 (2015)
Keun-Young Kim et al.
Cell reports, 29(3), 628-644 (2019-10-17)
The form and synaptic fine structure of melanopsin-expressing retinal ganglion cells, also called intrinsically photosensitive retinal ganglion cells (ipRGCs), were determined using a new membrane-targeted version of a genetic probe for correlated light and electron microscopy (CLEM). ipRGCs project to
Daniela Boassa et al.
Cell chemical biology, 26(10), 1407-1416 (2019-08-06)
A protein-fragment complementation assay (PCA) for detecting and localizing intracellular protein-protein interactions (PPIs) was built by bisection of miniSOG, a fluorescent flavoprotein derived from the light, oxygen, voltage (LOV)-2 domain of Arabidopsis phototropin. When brought together by interacting proteins, the

Global Trade Item Number

SKUGTIN
44612-500ML04061837837975
44612-100ML04061832284446

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