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Dokumente

08561

Sigma-Aldrich

(S)-(−)-α-Liponsäure

≥97% (HPLC)

Synonym(e):

(S)-1,2-Dithiolan-3-pentansäure, (S)-1,2-Dithiolan-3-valeriansäure, (S)-6,8-Thioctsäure

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About This Item

Empirische Formel (Hill-System):
C8H14O2S2
CAS-Nummer:
1077-27-6
Molekulargewicht:
206.33
Beilstein:
81852
MDL-Nummer:
MFCD01863481
UNSPSC-Code:
12352106
PubChem Substanz-ID:
329748605
NACRES:
NA.25

Assay

≥97% (HPLC)

Optische Reinheit

enantiomeric excess: ≥98.0% (HPLC)

Lagertemp.

−20°C

SMILES String

OC(=O)CCCC[C@H]1CCSS1

InChI

1S/C8H14O2S2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10)/t7-/m0/s1

InChIKey

AGBQKNBQESQNJD-ZETCQYMHSA-N

Biochem./physiol. Wirkung

Biological antioxidant with prooxidant activities . Method for enantioseparation of lipoic acid in dietary supplements by capillary electrophoresis.

Verpackung

Bottomless glass bottle. Contents are inside inserted fused cone.

Piktogramme

Exclamation mark
GHS07

Signalwort

Warning

H-Sätze

H302

Gefahreneinstufungen

Acute Tox. 4 Oral

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Slide 1 of 2

1 of 2

αα-Liponsäure α-Lipoic Acid, CAS 1077-28-7 is an oxidized form with antioxidant properties. Reduces renal lipid peroxidation in rats with cisplatin n-induced nephrotoxicity.

Sigma-Aldrich

437692

αα-Liponsäure

m-dPEG®8-Lipoamide

Sigma-Aldrich

QBD10800

m-dPEG®8-Lipoamide

Shuji Kodama et al.
Electrophoresis, 33(15), 2441-2445 (2012-08-14)
Lipoic acid, an antioxidant, naturally occurs as the (R)-enantiomer, while synthetic lipoic acid is racemic. It is thus of interest to know the (R)-enantiomer content of lipoic acid supplements. Here, we used capillary electrophoresis to directly enantioseparate lipoic acid in
Ronald Bentley
Chemical Society reviews, 34(7), 609-624 (2005-06-21)
Chiral structures profoundly influence chemical and biological processes. While chiral carbon biomolecules have received much attention, chirality is also possible in certain sulfur compounds; just as with carbon, there can be differences in the physiological behavior of chiral sulfur compounds.
L Packer et al.
Free radical biology & medicine, 19(2), 227-250 (1995-08-01)
alpha-Lipoic acid, which plays an essential role in mitochondrial dehydrogenase reactions, has recently gained considerable attention as an antioxidant. Lipoate, or its reduced form, dihydrolipoate, reacts with reactive oxygen species such as superoxide radicals, hydroxyl radicals, hypochlorous acid, peroxyl radicals
Hadi Moini et al.
Toxicology and applied pharmacology, 182(1), 84-90 (2002-07-20)
Reactive oxygen (ROS) and nitrogen oxide (RNOS) species are produced as by-products of oxidative metabolism. A major function for ROS and RNOS is immunological host defense. Recent evidence indicate that ROS and RNOS may also function as signaling molecules. However

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