The solubility of this product has not been determined. However, the cell culture tested (±)-α-Lipoic acid, product T1395, is soluble at 50 mg/mL in ethanol. Similar solubility is expected for this item. In addition, various sources indicate this compound is also soluble in DMSO, acetonitrile, and chloroform. This information has not been validated.
Fortfahren mit
07039
(R)-(+)-α-Liponsäure
≥98.0% (HPLC)
Synonym(e):
(R)-(+)-1,2-Dithiolan-3-valeriansäure, (R)-6,8-Dithiooctansäure, (R)-6,8-Thioctsäure
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| Packungsgröße | SKU | Verfügbarkeit | Preis |
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Über diesen Artikel
Empirische Formel (Hill-System):
C8H14O2S2
CAS-Nummer:
Molekulargewicht:
206.33
UNSPSC Code:
12352202
PubChem Substance ID:
NACRES:
NA.32
MDL number:
Preise und Verfügbarkeit sind derzeit nicht verfügbar.
Technischer Dienst
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Unterstützung erhaltenQuality Level
assay
≥98.0% (HPLC)
optical purity
enantiomeric excess: ≥98.0% (HPLC)
mp
48-52 °C (lit.)
storage temp.
−20°C
InChI
1S/C8H14O2S2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10)/t7-/m1/s1
InChI key
AGBQKNBQESQNJD-SSDOTTSWSA-N
Biochem/physiol Actions
(R)-(+)-α-Lipoic acid was shown to significantly increase pyruvate oxidation while abrogating fatty acid oxidation in rat hepatocytes. These effects make R-(+)-α-Lipoic acid a promising treatment option for the treatment of Type II diabetes.[1] It is a biological antioxidant with prooxidant activities[2][3], its therapeutic potential is widely investigated[4][5][6], e.g. in the treatment for Alzheimer′s disease.[7]
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Analysis Note
identity confirmed by LC-MS
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Dieser Artikel | |||
|---|---|---|---|
| Quality Level 100 | Quality Level 100, 200 | Quality Level 100 | Quality Level - |
| assay ≥98.0% (HPLC) | assay ≥97% (HPLC) | assay ≥98.0% (HPLC) | assay - |
| storage temp. −20°C | storage temp. −20°C | storage temp. 2-8°C | storage temp. 2-8°C |
| mp 48-52 °C (lit.) | mp - | mp 48-52 °C (lit.) | mp - |
| optical purity enantiomeric excess: ≥98.0% (HPLC) | optical purity enantiomeric excess: ≥98.0% (HPLC) | optical purity - | optical purity - |
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Lagerklasse
11 - Combustible Solids
wgk
WGK 3
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Jennie L Walgren et al.
Metabolism: clinical and experimental, 53(2), 165-173 (2004-02-10)
R-(+)-alpha-lipoic acid (R-LA) is the naturally occurring enantiomer of LA. It is a strong antioxidant and cofactor of key metabolic enzyme complexes catalyzing the decarboxylation of alpha-keto acids. Racemic LA (rac-LA) has shown promise in treating diabetic polyneuropathy, and some
Dove J Keith et al.
Pharmacological research, 66(3), 199-206 (2012-05-23)
Lipoic acid (LA) shows promise as a beneficial micronutrient toward improving elder health. Studies using old rats show that (R)-α-LA (R-LA) significantly increases low molecular weight antioxidants that otherwise decline with age. Despite this rationale for benefiting human health, little
Annette Maczurek et al.
Advanced drug delivery reviews, 60(13-14), 1463-1470 (2008-07-29)
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that destroys patient memory and cognition, communication ability with the social environment and the ability to carry out daily activities. Despite extensive research into the pathogenesis of AD, a neuroprotective treatment -
Global Trade Item Number
| SKU | GTIN |
|---|---|
| N17351-500G | 04061832113487 |
| N17351-100G | 04061832113463 |
| 07039-10MG | 04061838647375 |
| 07039-50MG | 04061833380390 |
| 07039-500MG | 04061833380383 |
| 7039 | 04061838245526 |
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What is REF 07039 Lipoic Acid soluble in?
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