08450

7-Amino-4-methyl-3-cumarinessigsäure-N-succinimidylester

BioReagent, suitable for fluorescence, ≥90% (HPLC)

• Synonym(e): 7-(Dimethylamino)-cumarin-4-essigsäure-NHS, 7-Amino-4-methyl-3-cumarinessigsäure-N-succinimidylester, 7-Amino-4-methyl-3-cumarinylacetyl, N-Succinimidyl-7-amino-4-methyl-3-cumarinylacetat, AMCA-NHS, Succinimidyl-7-amino-4-methylcumarin-3-acetat
• Empirische Formel (Hill-System): C₁₆H₁₄N₂O₆
• CAS-Nummer: 113721-87-2
• Molekulargewicht: 330.29
• Beilstein: 9007679
• MDL-Nummer: MFCD00036170
• UNSPSC-Code: 12352108
• PubChem Substanz-ID: 329748586
• NACRES: NA.32

Eigenschaften

• Produktlinie: BioReagent
• Assay: ≥90% (HPLC)
• Löslichkeit: DMF: soluble; DMSO: soluble
• Fluoreszenz: λ_ex 354 nm; λ_em 440 nm in methanol
• Eignung: suitable for fluorescence
• Lagertemp.: −20°C
• SMILES String: CC1=C(CC(=O)ON2C(=O)CCC2=O)C(=O)Oc3cc(N)ccc13
• InChI: 1S/C16H14N2O6/c1-8-10-3-2-9(17)6-12(10)23-16(22)11(8)7-15(21)24-18-13(19)4-5-14(18)20/h2-3,6H,4-5,7,17H2,1H3
• InChIKey: ILKQVTIMOGNSAS-UHFFFAOYSA-N

Beschreibung

Anwendung

AMCA-NHS has been utilized in the development of a donor europium chelate fluorochrome for use in LRET based analyses by first reacting with an amino group and then with DTPA anhydride . Utilized in FRET based studies, acting as the donor dye and can be paired with fluorescein-5-isothiocyanate as the acceptor dye . A blue fluorescent dye reactive towards primary amine groups on proteins, peptides, antibodies, and other biomolecules (at pH 7.0-9.0).

Verpackung

Bottomless glass bottle. Contents are inside inserted fused cone.

Sonstige Hinweise

Labeling of lysyl residues in proteins

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves