03907

Tioconazol

97%

• Synonym(e): 1-{2-[(2-Chlor-3-thienyl)-methoxy]-2-(2,4-dichlor-phenyl)-ethyl}-1H-imidazol, Thioconazol
• Empirische Formel (Hill-System): C₁₆H₁₃Cl₃N₂OS
• CAS-Nummer: 65899-73-2
• Molekulargewicht: 387.71
• PubChem Substance ID: 329747834
• UNSPSC Code: 51302325
• NACRES: NA.85
• EC Number: 265-973-8
• MDL number: MFCD00057276

Eigenschaften

• Quality Segment: 100
• assay: ≥96.5% (HPLC), 96.5-103.5% (NT), 97%
• form: powder
• color: white to off-white
• antibiotic activity spectrum: fungi, yeast
• mode of action: cell membrane | interferes
• SMILES string: Clc1ccc(C(Cn2ccnc2)OCc3ccsc3Cl)c(Cl)c1
• InChI: 1S/C16H13Cl3N2OS/c17-12-1-2-13(14(18)7-12)15(8-21-5-4-20-10-21)22-9-11-3-6-23-16(11)19/h1-7,10,15H,8-9H2
• InChI key: QXHHHPZILQDDPS-UHFFFAOYSA-N

Beschreibung

General description

Chemical structure: pyrimidine

Application

Tioconazole was used to study the synergistic mechanisms of antifungals on Candida albicans as well as significant drug-drug interactions in vivo[1].

Biochem/physiol Actions

Tioconazol ist ein Antipilzmedikament, das wirksamer als Fluconazol oder Voriconazol gegenüber Candida glabrata -Mutantenstämmen ist. Sein Wirkungsmechanismus beruht auf Membranzerstörung und Verlust der intrazellulären ATP.

Packaging

10G

Other Notes

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

Sicherheitshinweise

• pictograms: GHS08,GHS07,GHS09
• signalword: Warning
• hcodes: H302,H317,H361d,H410
• pcodes: P202 - P273 - P280 - P301 + P312 - P302 + P352 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 2 - Skin Sens. 1
• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves