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Merck

F8798

Sigma-Aldrich

Folsäure

meets USP testing specifications

Synonym(e):

PteGlu, Pteroyl-L-glutaminsäure, Vitamin M

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5 G
€ 43,70
25 G
€ 106,00
100 G
€ 345,00

€ 43,70


Voraussichtliches Versanddatum31. Mai 2025


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5 G
€ 43,70
25 G
€ 106,00
100 G
€ 345,00

About This Item

Empirische Formel (Hill-System):
C19H19N7O6
CAS-Nummer:
Molekulargewicht:
441.40
Beilstein:
100781
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352100
eCl@ss:
34058014
PubChem Substanz-ID:
NACRES:
NA.21

€ 43,70


Voraussichtliches Versanddatum31. Mai 2025


Bulk-Bestellung anfordern

Biologische Quelle

synthetic (organic)

Qualitätsniveau

Agentur

USP/NF
meets USP testing specifications

Assay

97.0-102.0% dry basis

Form

solid

Farbe

yellow

mp (Schmelzpunkt)

>285 °C

Anwendung(en)

cell analysis
pharmaceutical (small molecule)

Funktionelle Gruppe

amide
amine
carboxylic acid

SMILES String

NC(N1)=NC(C2=C1N=CC(CNC3=CC=C(C(N[C@@H](CCC(O)=O)C(O)=O)=O)C=C3)=N2)=O

InChI

1S/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s1

InChIKey

OVBPIULPVIDEAO-LBPRGKRZSA-N

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Allgemeine Beschreibung

Folic acid, also known as pteroyl-L-glutamic acid, belongs to the vitamin B group. The conformational analysis of folic acid in the solution has been reported based on nuclear magnetic resonance (NMR) and theoretical calculations.[1] The reaction kinetics of the photodecomposition under ultraviolet radiation has been investigated.[2] This product is a high quality pharmacopoeia product that meets the testing specifications of USP (United States Pharmacopoeia). It can be employed in research and pilot studies.

Anwendung

Folic acid has been used in a study to investigate its protective effects against the toxicity caused by valproic acid (VPA) on maternal liver tissue.[3] It has also been used as standard for the quantification of plasma folic acid by reversed-phase HPLC.[4]

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


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Die Dokumentenbibliothek aufrufen

Solution structure of folic acid: Molecular mechanics and NMR investigation.
Bonechi C, et al.
Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy, 60(7), 1411-1419 (2004)
Ultrastructural investigation of the protective role of folic acid and vitamin E against toxic effects of valproic acid on maternal liver tissue during period of gestation.
Ozlem P Baran et al.
Saudi medical journal, 27(3), 407-409 (2006-03-15)
Ultraviolet photodegradation of folic acid.
Off MK, et al.
Journal of Photochemistry and Photobiology. B, Biology, 80(1), 47-55 (2005)
Carolyn Tam et al.
Obstetrics and gynecology international, 2012, 485179-485179 (2012-04-25)
There are increasing concerns that exposure to unmetabolized folic acid, which results from folic acid intakes that overwhelm the liver's metabolic capacity, may be associated with adverse effects. In this paper, we examined the folic acid status of women of
Tor A Strand et al.
Pediatrics, 135(4), e918-e926 (2015-03-25)
Folate and vitamin B-12 are important for growth. Many children in low- and middle-income countries have inadequate intakes of these nutrients. We undertook a randomized, placebo controlled double-blind trial in 1000 North Indian children, 6 to 35 months of age

Artikel

Explore folic acid importance in serum-free eukaryotic cell cultures, including CHO cells, and its role in media supplementation.

Questions

1–2 of 2 Questions  
  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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