BP617

Aspirin

British Pharmacopoeia (BP) Reference Standard

• Synonym(e): Acetylsalicylsäure, 2-Acetoxybenzoesäure, ASA, Aspirin
• Lineare Formel: 2-(CH₃CO₂)C₆H₄CO₂H
• CAS-Nummer: 50-78-2
• Molekulargewicht: 180.16
• EC Number: 200-064-1
• UNSPSC Code: 41116107
• NACRES: NA.24
• Beilstein/REAXYS Number: 779271
• MDL number: MFCD00002430

Eigenschaften

• grade: pharmaceutical primary standard
• API family: aspirin
• form: crystalline
• shelf life: limited shelf life, expiry date on the label
• manufacturer/tradename: BP
• mp: 134-136 °C (lit.)
• application(s): pharmaceutical; pharmaceutical small molecule
• format: neat
• storage temp.: 2-8°C
• SMILES string: CC(=O)Oc1ccccc1C(O)=O
• InChI: 1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12)
• InChI key: BSYNRYMUTXBXSQ-UHFFFAOYSA-N
• Gene Information: human ... PTGS1(5742), PTGS2(5743)

Beschreibung

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Aspirin BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:

Aspirin Tablets

Aspirin Gastro-resistant Tablets

Co-codaprin Tablets

Aspirin Dispersible Tablets

Aspirin and Caffeine Tablets

Biochem/physiol Actions

Verhindert durch Hemmung der Cyclooxygenase (Prostaglandin H Synthase) die Produktion von Prostaglandinen mit höher Selektivität für COX-1. Für den antithrombotischen Effekt ist die Hemmung von COX-1 in Thrombozyten verantwortlich, welches die Produktion von Thromboxan und die Blutplättchenaggregation hemmt. Chemopräventive Wirkung gegenüber kolorektalen und anderen soliden Tumoren.

Packaging

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

Other Notes

Sales restrictions may apply.

Sicherheitshinweise

• pictograms: GHS07
• signalword: Warning
• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 1
• flash_point_f: 482.0 °F
• flash_point_c: 250 °C
• hcodes: H302,H412
• pcodes: P264 - P270 - P273 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 3