77608

Phenol

BioUltra, Molecular Biology, ≥99.5% (GC)

• Synonym(e): ‘Carbolsäure’
• Lineare Formel: C₆H₅OH
• CAS-Nummer: 108-95-2
• Molekulargewicht: 94.11
• UNSPSC Code: 12352104
• NACRES: NA.25
• PubChem Substance ID: 329767806
• EC Number: 203-632-7
• Beilstein/REAXYS Number: 969616
• MDL number: MFCD00002143
• Assay: ≥99.5% (GC)
• Form: solid

Eigenschaften

• grade: Molecular Biology
• Quality Segment: 100
• vapor density: 3.24 (vs air)
• vapor pressure: 0.09 psi ( 55 °C), 0.36 mmHg ( 20 °C)
• product line: BioUltra
• assay: ≥99.5% (GC)
• form: solid
• autoignition temp.: 1319 °F
• contains: ~0.15% hypophosphorous acid as stabilizer
• expl. lim.: 8.6 %
• impurities: DNases, none detected, RNases, none detected, insoluble matter, passes filter test, phosphatases, none detected, proteases, none detected, ≤0.5% water
• ign. residue: ≤0.05%
• pH: 3.0-6.0 (25 °C, 0.5 M in H₂O)
• bp: 182 °C (lit.)
• mp: 40-42 °C
• solubility: H₂O: 0.5 M at 20 °C, clear, colorless
• density: 1.071 g/mL at 25 °C (lit.)
• anion traces: chloride (Cl^-): ≤5 mg/kg, sulfate (SO₄^2-): ≤50 mg/kg
• SMILES string: Oc1ccccc1
• cation traces: Al: ≤5 mg/kg, As: ≤0.1 mg/kg, Ba: ≤5 mg/kg, Bi: ≤5 mg/kg, Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤50 mg/kg, Li: ≤5 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Mo: ≤5 mg/kg, Na: ≤50 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Sr: ≤5 mg/kg, Zn: ≤5 mg/kg
• absorption: cut-off at 294 nm in H₂O at 0.5 M
• suitability: suitable for molecular biology
• storage temp.: 2-8°C
• InChI: 1S/C6H6O/c7-6-4-2-1-3-5-6/h1-5,7H
• InChI key: ISWSIDIOOBJBQZ-UHFFFAOYSA-N

Beschreibung

General description

Phenol/carbolic acid is mainly produced by hospital pharmacy as it is unavailable in premixed liquid form. It is not highly soluble in water. Phenol should be refrigerated and protected from light exposure to maintain its shelf life of approximately one year. Kidneys can excrete phenol as several conjugated derivatives.

Application

Phenol has been used in the incubation of pellet for RNA extraction.

Biochem/physiol Actions

Phenol has the ability to denature protein, hence can lead to denervation. At lower concentration, it can serve as a local anaesthetic and can also act as a neurolytic agent in higher concentration. It is also linked with tissue damage at higher concentrations.

Other Notes

Für die Präparation von DNA ; Phenolextraktionen im Klein- und Großmaßstab [1]

Sicherheitshinweise

• pictograms: GHS06,GHS08,GHS05,GHS09
• signalword: Danger
• hcodes: H301 + H311 + H331,H314,H341,H373,H411
• pcodes: P260 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Muta. 2 - Skin Corr. 1B - STOT RE 2
• target_organs: Nervous system,Kidney,Liver,Skin
• Lagerklasse: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk: WGK 2
• flash_point_f: 174.2 °F - closed cup
• flash_point_c: 79.0 °C - closed cup
• ppe: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges