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63187

Methoxypolyethylenglykol-maleimid

≥90% (NMR), 5,000

Synonym(e):

MeO-PEG-Mal, Monomethyl-polyethylenglykol-2-maleimid-ethylether, PEG-Maleimid

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Über diesen Artikel

CAS-Nummer:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.25
MDL number:
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Quality Level

assay

≥90% (NMR)

mol wt

PEG average Mn 5,000

Ω-end

maleimide

α-end

methoxy

storage temp.

−20°C

Application

Methoxypolyethylenglykol-maleimid (MeO-PEG-Mal) wird als Reagenz für die Proteinpegylierung verwendet. Unter PEGylierung wird der Vorgang der kovalenten Bindung von Polyethylenglykol(PEG)-Polymerketten an andere Moleküle, wie Proteine verstanden.

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Dieser Artikel
71255871246985973
assay

≥90% (NMR)

assay

-

assay

-

assay

≥80% (NMR)

Quality Level

200

Quality Level

100

Quality Level

100

Quality Level

200

mol wt

PEG average Mn 5,000

mol wt

PEG average Mn 750

mol wt

PEG average Mn 10,000 g/mol

mol wt

PEG average Mn 5,000

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

Ω-end

maleimide

Ω-end

maleimide

Ω-end

maleimide

Ω-end

NHS ester

α-end

methoxy

α-end

methoxy

α-end

methoxy

α-end

methoxy


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Lagerklasse

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Jiankun Qie et al.
Drug metabolism letters, 1(3), 232-240 (2007-08-01)
Site-specific mono-PEGylations were performed in different conformational regions of Thymosin alpha 1 (T alpha 1) by introducing one cysteine residue into the chosen site and coupling with thiol-specific mPEG-MAL reagent. Results demonstrated that PEGylated sites and regions influenced the conformations
R J Goodson et al.
Bio/technology (Nature Publishing Company), 8(4), 343-346 (1990-04-01)
We have modified recombinant interleukin-2 (rIL-2) to facilitate site-directed covalent attachment of monomethoxy polyethylene glycol (PEG). The site chosen for modification and subsequent covalent attachment with PEG (PEGylation) was the single glycosylation position found in the native interleukin-2 (IL-2). The
Lidia Wrobel et al.
Scientific reports, 6, 27484-27484 (2016-06-07)
Disulfide bond formation is crucial for the biogenesis and structure of many proteins that are localized in the intermembrane space of mitochondria. The importance of disulfide bond formation within mitochondrial proteins was extended beyond soluble intermembrane space proteins. Tim22, a



Global Trade Item Number

SKUGTIN
V0384-100MG04061837428913
V0384-1G04061826659700
63187-5G04061832887661
63187-1G04061832721262

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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