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46429

Methimazol

VETRANAL®, analytical standard

Synonym(e):

1-Methyl-2-imidazolthiol, 2-Mercapto-1-methylimidazol

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PackungsgrößeSKUVerfügbarkeitPreis
250 mg
Warenkorb auf Verfügbarkeit prüfen
€ 60,50

Über diesen Artikel

Empirische Formel (Hill-System):
C4H6N2S
CAS-Nummer:
Molekulargewicht:
114.17
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
200-482-4
Beilstein/REAXYS Number:
108646
MDL number:

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grade

analytical standard

Quality Level

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

144-147 °C (lit.)

application(s)

cleaning products
clinical
cosmetics
food and beverages
forensics and toxicology
personal care
pharmaceutical (small molecule)

format

neat

SMILES string

CN1C=CNC1=S

InChI

1S/C4H6N2S/c1-6-3-2-5-4(6)7/h2-3H,1H3,(H,5,7)

InChI key

PMRYVIKBURPHAH-UHFFFAOYSA-N

Gene Information

human ... TPO(7173)

General description

Methimazole is a thyreostatic compound, and an antihormone, which is widely used in medicine for the treatment of hyperthyroidism.

Application

Methimazole may be used as a reference standard for the determination of the analyte in fish homogenates using mixed mode solid-phase extraction technique with reversed-phase high-performance liquid chromatography method with ultraviolet detection (MMSPE-RP-HPLC-UV).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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Dieser Artikel
M85061411005Y0000336
Methimazole United States Pharmacopeia (USP) Reference Standard

USP

1411005

Methimazole

Thiamazole European Pharmacopoeia (EP) Reference Standard

Y0000336

Thiamazole

application(s)

cleaning products
clinical
cosmetics
food and beverages
forensics and toxicology
personal care
pharmaceutical (small molecule)

application(s)

cleaning products
cosmetics
food and beverages
forensics and toxicology
personal care
pharmaceutical (small molecule)
veterinary

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

technique(s)

-

format

neat

format

neat

format

neat

format

neat

Quality Level

200

Quality Level

200

Quality Level

-

Quality Level

-

grade

analytical standard

grade

analytical standard

grade

pharmaceutical primary standard

grade

pharmaceutical primary standard

shelf life

limited shelf life, expiry date on the label

shelf life

-

shelf life

-

shelf life

-


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pictograms

Health hazardExclamation mark

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

target_organs

Endocrine system

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 1A - Skin Sens. 1 - STOT RE 2

Lagerklasse

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects



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Stijn L J Van Herck et al.
The Journal of endocrinology, 218(1), 105-115 (2013-04-24)
Methimazole (MMI) is an anti-thyroid drug used in the treatment of chronic hyperthyroidism. There is, however, some debate about its use during pregnancy as MMI is known to cross the mammalian placenta and reach the developing foetus. A similar problem
Mal-Soon Shin et al.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 31(3), 214-223 (2013-01-19)
Thyroid hormones play a crucial role in new neuron production and maturation during brain development. Physical exercise is known to promote cell survival and functional recovery after brain injuries. In the present study, we investigated the effects of treadmill exercise
Yi Wang et al.
Toxicology and applied pharmacology, 271(2), 257-265 (2013-05-28)
Neurotoxicity of iodine deficiency-induced hypothyroidism during developmental period results in serious impairments of brain function, such as learning and memory. These impairments are largely irreversible, and the underlying mechanisms remain unclear. In addition to hypothyroidism, iodine deficiency may cause hypothyroxinemia



Global Trade Item Number

SKUGTIN
46429-250MG04061834089452

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