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Merck

34091

Supelco

Flubendazol

VETRANAL®, analytical standard

Synonym(e):

Flumoxanal, Methyl-[5-(4-fluorbenzoyl)-1H-benzimidazol-2-yl]-carbamat

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100 MG
€ 192,00

€ 192,00


Voraussichtliches Versanddatum02. Juni 2025


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100 MG
€ 192,00

About This Item

Empirische Formel (Hill-System):
C16H12FN3O3
CAS-Nummer:
Molekulargewicht:
313.28
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.24

€ 192,00


Voraussichtliches Versanddatum02. Juni 2025


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Qualität

analytical standard

Qualitätsniveau

Produktlinie

VETRANAL®

Haltbarkeit

limited shelf life, expiry date on the label

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Anwendung(en)

forensics and toxicology
pharmaceutical (small molecule)

Format

neat

SMILES String

COC(=O)Nc1nc2cc(ccc2[nH]1)C(=O)c3ccc(F)cc3

InChI

1S/C16H12FN3O3/c1-23-16(22)20-15-18-12-7-4-10(8-13(12)19-15)14(21)9-2-5-11(17)6-3-9/h2-8H,1H3,(H2,18,19,20,22)

InChIKey

CPEUVMUXAHMANV-UHFFFAOYSA-N

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Allgemeine Beschreibung

Flubendazol is a broad spectrum anthelmintic, which belongs to the class of compounds known as benzimidazoles.[1][2] It can be widely used in veterinary and human medicine.[3] It mainly finds applications in deworming poultry[1][2], swine[1][2], dogs and cats.[2]
Flubendazol is an injectable benzimidazole drug; though it is poorly absorbed it is quite effective in the treatment of trycocephalus, ascaris and oxyuriasis in both children and adults.[4]

Anwendung

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
VETRANAL® analytical standard can be used in the liquid chromatography coupled to mass spectrometry (LC-MS/MS) procedure, performed for the analysis of macrocyclic lactones in milk.[5]

Rechtliche Hinweise

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 2

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


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Kunden haben sich ebenfalls angesehen

Gabriel Rübensam et al.
Analytica chimica acta, 705(1-2), 24-29 (2011-10-04)
In this work a method is proposed and demonstrated for the analysis of the macrocyclic lactones abamectin, doramectin, eprinomectin, ivermectin and moxidectin in bovine milk by liquid chromatography coupled to mass spectrometry (LC-MS/MS) and liquid chromatography with fluorescence detection (LC-FL).
Paul A Spagnuolo et al.
Blood, 115(23), 4824-4833 (2010-03-30)
On-patent and off-patent drugs with previously unrecognized anticancer activity could be rapidly repurposed for this new indication given their prior toxicity testing. To identify such compounds, we conducted chemical screens and identified the antihelmintic flubendazole. Flubendazole induced cell death in
H Bártíková et al.
Journal of veterinary pharmacology and therapeutics, 33(1), 56-62 (2010-05-07)
The aim of this project was to study the influence of haemonchosis, a common parasitic infection of small ruminants caused by Haemonchus contortus, on the activity of biotransformation enzymes and on in vitro flubendazole (FLU) biotransformation in liver and small
V Krízová et al.
Journal of veterinary pharmacology and therapeutics, 32(6), 606-612 (2010-05-07)
Flubendazole (FLU) is indicated for control of helminthoses in pig and avian species (monogastric animals) and its corresponding pharmacokinetics are well known. The information on FLU's pharmacokinetic behavior in animal species with forestomach (ruminants) has been limited although the use
Laura Ceballos et al.
Chemotherapy, 56(5), 386-392 (2010-10-16)
Cystic echinococcosis (CE) is an important public health problem worldwide. Flubendazole, administered in tablets, has shown poor in vivo efficacy against CE in humans. However, flubendazole prepared as a solution caused a marked reduction in hydatid cysts developed in mice.

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