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Heparin Natriumsalz aus Schweinedarm

endotoxin, free

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PackungsgrößeSKUVerfügbarkeitPreis
10 vials
Warenkorb auf Verfügbarkeit prüfen
€ 63,50
15 vials
Warenkorb auf Verfügbarkeit prüfen
€ 94,80

Über diesen Artikel

CAS-Nummer:
UNSPSC Code:
12352201
NACRES:
NA.21
MDL number:

€ 63,50


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biological source

Porcine intestinal mucosa

Quality Level

form

powder

usage

sufficient for 5 mL blood anticoagulant

packaging

preweighed vial of 300 USP units

impurities

endotoxin, free

color

beige

solubility

water: soluble 50 g/L, acetone: insoluble, alcohol: insoluble, benzene: insoluble, chloroform: insoluble, diethyl ether: insoluble

compatibility

for use with E-Toxate

storage temp.

room temp

SMILES string

[Na+].[S](=O)(=O)(NC1C(OC(C(C1O[S](=O)(=O)O)OC4OC(C(C(C4O[S](=O)(=O)O)O)O)C(=O)O)CO)OC2C(OC(C(C2O)O[S](=O)(=O)O)OC3C(OC(C(C3O)NC(=O)C)O)CO[S](=O)(=O)O)C(=O)O)O

InChI

1S/C26H42N2O37S5.Na/c1-4(30)27-7-9(31)13(6(56-23(7)39)3-55-67(43,44)45)58-26-19(65-70(52,53)54)12(34)16(20(62-26)22(37)38)60-24-8(28-66(40,41)42)15(63-68(46,47)48)14(5(2-29)57-24)59-25-18(64-69(49,50)51)11(33)10(32)17(61-25)21(35)36;/h5-20,23-26,28-29,31-

InChI key

JRTRSJGZMRQDHI-UHFFFAOYSA-N

Application

Heparin sodium salt from porcine intestinal mucosa has been used as a M199 medium supplement used for maintaining human umbilical vein endothelial cells.[1]

Biochem/physiol Actions

Heparin sodium salt is the salt form of heparinic acid and is a polymer classified as a mucopolysaccharide or a glycosoaminoglycan. It is an anticoagulant that produces its major anticoagulant effect by activating antithrombin. Heparin binds to antithrombin III, a naturally occurring plasma protease inhibitor and accelerates significantly the rate at which antithrombin III (AT-III) inhibits coagulation proteases (factor Xa and thrombin).[2][3][4] Additionally, it also facilitates the stabilization and regulation of tryptase as an enzymatically active tetramer.[5]

Other Notes

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Legal Information

E-Toxate is a trademark of Sigma-Aldrich Co. LLC

Disclaimer

Not for injection.

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1 of 1

Dieser Artikel
H3149H3393H5515
biological source

Porcine intestinal mucosa

biological source

Porcine intestinal mucosa

biological source

Porcine intestinal mucosa

biological source

Porcine intestinal mucosa

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

solubility

water: soluble 50 g/L, alcohol: insoluble, chloroform: insoluble, acetone: insoluble, diethyl ether: insoluble, benzene: insoluble

solubility

H2O: 50 mg/mL

solubility

H2O: 50 mg/mL, clear, colorless to faintly yellow

solubility

H2O: 50 mg/mL, clear, colorless to faintly yellow

form

powder

form

powder

form

powder

form

powder

storage temp.

room temp

storage temp.

-

storage temp.

room temp

storage temp.

room temp

impurities

endotoxin, free

impurities

-

impurities

-

impurities

-


Still not finding the right product?


Lagerklasse

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Analysenzertifikate (COA)

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Overexpression of Functional SLC6A3 in Clear Cell Renal Cell Carcinoma.
Jennifer Hansson et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 23(8), 2105-2115 (2016-09-25)
Mechanism of the anticoagulant action of heparin.
I Björk et al.
Molecular and cellular biochemistry, 48(3), 161-182 (1982-10-29)
D Beeler et al.
The Journal of biological chemistry, 254(8), 2902-2913 (1979-04-25)
Preparations of low molecular weight porcine heparin with an average specific anticoagulant activity of 94 units/mg were fractionated into "active" and "relatively inactive" forms of the mucopolysaccharide of approximately 6000 daltons each. The active fraction was further subdivided into various



Global Trade Item Number

SKUGTIN
19667-1G04061826651728
163244-5G04061838747495
163244-1G04061838747488
163244-25G04061832904320
19667-5G04061833353967
2106-15VL04061838771353
2106-10VL04061838771346

Questions

1–2 of 2 Questions  
  1. What is the molecular weight of Heparin sodium salt? Is this same with cat:H3149 or H3393?

    1 answer
    1. The molecular weight of porcine Heparin sodium may range from 6,000 to 30,000 Daltons, with most chains ranging from 16,000–19,000 Da. This product, as well as the H3393 and H3149, are derived from the same source and offer identical properties, including molecular weight.

      Helpful?

  2. Hola, Me gustaría saber cual es la cantidad de heparina en cada uno de los viales

    1 answer
    1. The minimum activity of this heparin product is 300 units per vial. This product is lyophilized from a prepared stock solution and the mass weight per vial is not available. However, the starting material used to produce this product has historically tested at approximately 200 units heparin per milligram. The mass weight per vial is expected to reflect this value, with each 300 unit vial containing approximately 1.5 mg.

      Helpful?

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